Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUV39H2
  • Mouse genes Suv39h2
  • Rat genes Suv39h2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Suv39h2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Suv39h2	IDA		Mouse	MGI:MGI:1927682|PMID:11094092
Molecular Function	GO:0140938	histone H3 methyltransferase activity	Suv39h2	IDA		Mouse	MGI:MGI:2176084|PMID:10949293
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	SUV39H2	IDA		Human	PMID:10949293
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Suv39h2	IGI	MGI:MGI:1099440	Mouse	PMID:15788566
Molecular Function	GO:0140947	histone H3K9me2 methyltransferase activity	Suv39h2	IGI	MGI:MGI:1099440	Mouse	PMID:23451023
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q5T6S3	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8N5Z5	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8NEU8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8TBB5	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q9BXL8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q9UDV6	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q9Y605	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8NEU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:V9HWG0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8ND90	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SUV39H2	IPI	UniProtKB:Q8NEU8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Suv39h2	IPI	UniProtKB:O54943	Mouse	MGI:MGI:5569417|PMID:24413057
Molecular Function	GO:0008276	protein methyltransferase activity	Suv39h2	IDA		Mouse	PMID:11094092
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Suv39h2	IDA		Mouse	PMID:21402781
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	SUV39H2	IDA		Human	PMID:20084102
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Suv39h2	IDA		Mouse	MGI:MGI:5569417|PMID:24413057
Molecular Function	GO:0008270	zinc ion binding	SUV39H2	IDA		Human	PMID:20084102
Cellular Component	GO:0000785	chromatin	SUV39H2	IDA		Human	PMID:10949293
Cellular Component	GO:0000792	heterochromatin	Suv39h2	IDA		Mouse	PMID:11094092
Cellular Component	GO:0005634	nucleus	Suv39h2	IDA		Mouse	PMID:21402781
Biological Process	GO:0071456	cellular response to hypoxia	SUV39H2	IDA		Human	PMID:21402781
Biological Process	GO:0006325	chromatin organization	SUV39H2	IMP		Human	PMID:10949293
Biological Process	GO:0006338	chromatin remodeling	SUV39H2	IDA		Human	PMID:10949293
Biological Process	GO:0007623	circadian rhythm	Suv39h2	IMP		Mouse	MGI:MGI:5569417|PMID:24413057
Biological Process	GO:0007140	male meiotic nuclear division	Suv39h2	IEP		Mouse	MGI:MGI:1927682|PMID:11094092
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Suv39h2	IMP		Mouse	MGI:MGI:5569417|PMID:24413057
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	Suv39h2	IMP		Mouse	MGI:MGI:5569417|PMID:24413057
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SUV39H2	IMP		Human	PMID:21402781

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern