Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STXBP5
  • Mouse genes Stxbp5
  • Rat genes Stxbp5
  • Zfish genes stxbp5a,stxbp5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stxbp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Stxbp5	IPI	PR:O09044	Mouse	PMID:12832401
Molecular Function	GO:0019905	syntaxin binding	Stxbp5	IPI	PR:P70452	Mouse	PMID:12832401
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp5	IDA		Mouse	MGI:MGI:3654783|PMID:16787939
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp5	IPI	PR:O35526	Mouse	PMID:12832401
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp5	IDA		Rat	PMID:9620695|RGD:1299498
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Stxbp5	IDA		Mouse	PMID:12832401
Cellular Component	GO:0005829	cytosol	STXBP5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098674	extrinsic component of neuronal dense core vesicle membrane	Stxbp5	IDA		Mouse	PMID:28746398
Cellular Component	GO:0098674	extrinsic component of neuronal dense core vesicle membrane	Stxbp5	IMP		Mouse	PMID:28746398
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Stxbp5	IDA		Rat	PMID:9620695|RGD:1299498
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Stxbp5	IDA		Mouse	PMID:18936251
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Stxbp5	IMP		Mouse	PMID:18936251
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Stxbp5	IEP		Mouse	PMID:18936251
Cellular Component	GO:0031594	neuromuscular junction	Stxbp5	IDA		Rat	PMID:9620695|RGD:1299498
Cellular Component	GO:0098793	presynapse	Stxbp5	IDA		Mouse	PMID:28746398
Cellular Component	GO:0098793	presynapse	Stxbp5	IDA		Rat	PMID:16186257|RGD:155230701
Cellular Component	GO:0099523	presynaptic cytosol	Stxbp5	IDA		Rat	PMID:9620695|RGD:1299498
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stxbp5	IDA		Rat	PMID:9620695|RGD:1299498
Cellular Component	GO:0008021	synaptic vesicle	Stxbp5	EXP		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0008021	synaptic vesicle	Stxbp5	IDA		Rat	PMID:17110340|RGD:12050113
Biological Process	GO:0006887	exocytosis	Stxbp5	IDA		Mouse	PMID:12832401
Biological Process	GO:0045921	positive regulation of exocytosis	Stxbp5	IDA		Mouse	MGI:MGI:3654783|PMID:16787939
Biological Process	GO:0017157	regulation of exocytosis	Stxbp5	IDA		Mouse	PMID:21330375
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Stxbp5	IMP		Mouse	PMID:18936251
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Stxbp5	IDA		Mouse	PMID:18936251
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Stxbp5	IEP		Mouse	PMID:18936251
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Stxbp5	IMP		Mouse	PMID:18936251
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Stxbp5	IDA		Mouse	PMID:18936251
Biological Process	GO:0099504	synaptic vesicle cycle	Stxbp5	IDA		Rat	PMID:27807164|RGD:13702312
Biological Process	GO:0099504	synaptic vesicle cycle	Stxbp5	IMP		Rat	PMID:27807164|RGD:13702312

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern