Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STIL
  • Mouse genes Stil
  • Rat genes Stil
  • Zfish genes stil
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stil

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	STIL	IPI	UniProtKB:Q15468	Human	PMID:22020124
Molecular Function	GO:0042802	identical protein binding	STIL	IPI	UniProtKB:Q15468	Human	PMID:26188084
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q6UVJ0	Human	PMID:22020124
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q9HC77	Human	PMID:22020124
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q9HC77	Human	PMID:24076405
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q96PK6	Human	PMID:25385835
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q9HC77	Human	PMID:25385835
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:O00444	Human	PMID:26188084
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q6UVJ0	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	STIL	IPI	UniProtKB:Q9HC77	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	Stil	IPI	UniProtKB:Q13526	Mouse	PMID:16024801
Molecular Function	GO:0005515	protein binding	stil	IPI	UniProtKB:E7FCY1	Zfish	PMID:24076405|ZFIN:ZDB-PUB-200522-23
Molecular Function	GO:0005515	protein binding	stil	IPI	ZFIN:ZDB-GENE-030131-6323	Zfish	PMID:24052813
Cellular Component	GO:0005814	centriole	STIL	IDA		Human	PMID:22020124
Cellular Component	GO:0005814	centriole	STIL	IDA		Human	PMID:22349705
Cellular Component	GO:0005814	centriole	STIL	IDA		Human	PMID:25385835
Cellular Component	GO:0005813	centrosome	STIL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	STIL	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	STIL	IDA		Human	PMID:22349705
Cellular Component	GO:0005737	cytoplasm	STIL	IDA		Human	PMID:22020124
Cellular Component	GO:0005737	cytoplasm	STIL	IDA		Human	PMID:22349705
Cellular Component	GO:0005654	nucleoplasm	STIL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0120099	procentriole replication complex	STIL	IPI		Human	PMID:22020124
Biological Process	GO:0006915	apoptotic process	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0010171	body morphogenesis	stil	IMP	ZFIN:ZDB-GENO-020430-12	Zfish	PMID:12006978
Biological Process	GO:0051298	centrosome duplication	STIL	IDA		Human	PMID:22349705
Biological Process	GO:0051298	centrosome duplication	STIL	IMP		Human	PMID:22349705
Biological Process	GO:0051298	centrosome duplication	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:22349705
Biological Process	GO:0007368	determination of left/right symmetry	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0000578	embryonic axis specification	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0033504	floor plate development	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0030900	forebrain development	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0001947	heart looping	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0001701	in utero embryonic development	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0071174	mitotic spindle checkpoint signaling	Stil	IMP		Mouse	PMID:16024801
Biological Process	GO:0007052	mitotic spindle organization	STIL	IMP		Human	PMID:22349705
Biological Process	GO:0007052	mitotic spindle organization	stil	IMP	ZFIN:ZDB-GENO-080124-6	Zfish	PMID:17576815
Biological Process	GO:0007052	mitotic spindle organization	stil	IMP	ZFIN:ZDB-GENO-070711-2	Zfish	PMID:17576815
Biological Process	GO:0035264	multicellular organism growth	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0043066	negative regulation of apoptotic process	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0001843	neural tube closure	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0021915	neural tube development	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0070050	neuron cellular homeostasis	stil	IMP	ZFIN:ZDB-GENO-130308-2	Zfish	PMID:23166330
Biological Process	GO:0070050	neuron cellular homeostasis	stil	IMP	ZFIN:ZDB-MRPHLNO-130308-1	Zfish	PMID:23166330
Biological Process	GO:1905515	non-motile cilium assembly	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:22349705
Biological Process	GO:0030903	notochord development	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0046601	positive regulation of centriole replication	STIL	IDA		Human	PMID:22020124
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Stil	IMP		Mouse	PMID:16024801
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	STIL	IDA		Human	PMID:22020124
Biological Process	GO:0071539	protein localization to centrosome	STIL	IMP		Human	PMID:22349705
Biological Process	GO:0046599	regulation of centriole replication	STIL	IMP		Human	PMID:22020124
Biological Process	GO:0007224	smoothened signaling pathway	Stil	IMP	MGI:MGI:2152962	Mouse	PMID:10385121
Biological Process	GO:0007224	smoothened signaling pathway	stil	IGI	ZFIN:ZDB-MRPHLNO-060828-2,ZFIN:ZDB-MRPHLNO-130308-1	Zfish	PMID:23166330
Biological Process	GO:0051225	spindle assembly	stil	IMP	ZFIN:ZDB-GENO-070711-2	Zfish	PMID:17576815
Biological Process	GO:0051225	spindle assembly	stil	IMP	ZFIN:ZDB-GENO-080124-6	Zfish	PMID:17576815

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern