Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRR
  • Mouse genes Srr
  • Rat genes Srr
  • Zfish genes srr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	SRR	IDA		Human	PMID:20106978
Molecular Function	GO:0005524	ATP binding	Srr	IDA		Mouse	PMID:17293453
Molecular Function	GO:0005524	ATP binding	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Molecular Function	GO:0005509	calcium ion binding	Srr	IDA		Mouse	PMID:12021263
Molecular Function	GO:0016594	glycine binding	Srr	IDA		Mouse	PMID:15710237
Molecular Function	GO:0042802	identical protein binding	SRR	IPI	UniProtKB:Q9GZT4	Human	PMID:15681805
Molecular Function	GO:0042802	identical protein binding	SRR	IPI	UniProtKB:Q9GZT4	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Srr	IPI	PR:Q9QZX7	Mouse	PMID:12021263
Molecular Function	GO:0003941	L-serine ammonia-lyase activity	SRR	IDA		Human	PMID:18812225
Molecular Function	GO:0000287	magnesium ion binding	SRR	IDA		Human	PMID:20106978
Molecular Function	GO:0000287	magnesium ion binding	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Molecular Function	GO:0030165	PDZ domain binding	SRR	IPI	UniProtKB:Q9NRD5	Human	PMID:16314870
Molecular Function	GO:0005515	protein binding	SRR	IPI	UniProtKB:Q9H4P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Srr	IPI	PR:Q9QZX7	Mouse	PMID:12021263
Molecular Function	GO:0042803	protein homodimerization activity	SRR	IPI	UniProtKB:Q9GZT4	Human	PMID:20106978
Molecular Function	GO:0042803	protein homodimerization activity	Srr	IPI	UniProtKB:Q76EQ0	Rat	PMID:20106978|RGD:8554326
Molecular Function	GO:0030170	pyridoxal phosphate binding	SRR	IDA		Human	PMID:20106978
Molecular Function	GO:0030170	pyridoxal phosphate binding	Srr	IMP		Mouse	PMID:10557334
Molecular Function	GO:0030170	pyridoxal phosphate binding	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Molecular Function	GO:0030170	pyridoxal phosphate binding	Srr	IDA		Rat	PMID:9892700|RGD:2302218
Molecular Function	GO:0030378	serine racemase activity	SRR	IDA		Human	PMID:11054547
Molecular Function	GO:0030378	serine racemase activity	SRR	IDA		Human	PMID:15193426
Molecular Function	GO:0030378	serine racemase activity	SRR	IDA		Human	PMID:20106978
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Mouse	PMID:15710237
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Mouse	PMID:12021263
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Mouse	PMID:17293453
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Mouse	PMID:15536068
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Mouse	PMID:10557334
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Molecular Function	GO:0030378	serine racemase activity	Srr	IDA		Rat	PMID:9892700|RGD:2302218
Molecular Function	GO:0018114	threonine racemase activity	Srr	IDA		Mouse	PMID:15536068
Cellular Component	GO:0045177	apical part of cell	Srr	IDA		Rat	PMID:16289842|RGD:2302217
Cellular Component	GO:0005737	cytoplasm	SRR	IDA		Human	PMID:16314870
Cellular Component	GO:0005737	cytoplasm	Srr	IDA		Rat	PMID:16289842|RGD:2302217
Cellular Component	GO:0043025	neuronal cell body	SRR	IDA		Human	PMID:17880399
Cellular Component	GO:0005886	plasma membrane	Srr	IDA		Rat	PMID:16289842|RGD:2302217
Biological Process	GO:0007568	aging	Srr	IEP		Rat	PMID:16842499|RGD:2302214
Biological Process	GO:0007420	brain development	Srr	IEP		Rat	PMID:16739185|RGD:2302215
Biological Process	GO:0070179	D-serine biosynthetic process	SRR	IDA		Human	PMID:11054547
Biological Process	GO:0070179	D-serine biosynthetic process	SRR	IDA		Human	PMID:15193426
Biological Process	GO:0070179	D-serine biosynthetic process	Srr	IDA		Mouse	PMID:11054547
Biological Process	GO:0070179	D-serine biosynthetic process	Srr	IDA		Mouse	PMID:15710237
Biological Process	GO:0070179	D-serine biosynthetic process	Srr	IDA		Mouse	PMID:10557334
Biological Process	GO:0070179	D-serine biosynthetic process	Srr	IDA		Mouse	PMID:12021263
Biological Process	GO:0070178	D-serine metabolic process	SRR	IDA		Human	PMID:20106978
Biological Process	GO:0070178	D-serine metabolic process	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Biological Process	GO:0006563	L-serine metabolic process	SRR	IDA		Human	PMID:11054547
Biological Process	GO:0006563	L-serine metabolic process	SRR	IDA		Human	PMID:15193426
Biological Process	GO:0006563	L-serine metabolic process	SRR	IDA		Human	PMID:20106978
Biological Process	GO:0006563	L-serine metabolic process	Srr	IDA		Mouse	PMID:15710237
Biological Process	GO:0006563	L-serine metabolic process	Srr	IDA		Mouse	PMID:10557334
Biological Process	GO:0006563	L-serine metabolic process	Srr	IDA		Mouse	PMID:12021263
Biological Process	GO:0006563	L-serine metabolic process	Srr	IDA		Mouse	PMID:16517698
Biological Process	GO:0006563	L-serine metabolic process	Srr	IDA		Rat	PMID:20106978|RGD:8554326
Biological Process	GO:0042866	pyruvate biosynthetic process	SRR	IDA		Human	PMID:18812225
Biological Process	GO:0032496	response to lipopolysaccharide	SRR	IEP		Human	PMID:15681805
Biological Process	GO:0043278	response to morphine	Srr	IEP		Rat	PMID:18603832|RGD:2302212
Biological Process	GO:0014070	response to organic cyclic compound	Srr	IEP		Rat	PMID:16716293|RGD:2302216
Biological Process	GO:0009410	response to xenobiotic stimulus	Srr	IEP		Rat	PMID:17109841|RGD:2302213
Biological Process	GO:0009069	serine family amino acid metabolic process	Srr	IDA		Mouse	PMID:15536068

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern