Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRPX2
  • Mouse genes Srpx2
  • Rat genes Srpx2
  • Zfish genes srpx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srpx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036458	hepatocyte growth factor binding	SRPX2	IDA		Human	PMID:22242148
Molecular Function	GO:0042802	identical protein binding	SRPX2	IDA		Human	PMID:24179158
Molecular Function	GO:0005515	protein binding	SRPX2	IPI	UniProtKB:O75173	Human	PMID:18718938
Molecular Function	GO:0005515	protein binding	SRPX2	IPI	UniProtKB:P07858	Human	PMID:18718938
Molecular Function	GO:0005102	signaling receptor binding	SRPX2	IPI	UniProtKB:Q03405	Human	PMID:18718938
Molecular Function	GO:0005102	signaling receptor binding	Srpx2	IPI	UniProtKB:P35456	Mouse	MGI:MGI:4412425|PMID:19667118
Cellular Component	GO:0009986	cell surface	Srpx2	IDA		Rat	PMID:24179158|RGD:8553698
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SRPX2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Srpx2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	SRPX2	IDA		Human	PMID:19065654
Cellular Component	GO:0005737	cytoplasm	SRPX2	IDA		Human	PMID:9864177
Cellular Component	GO:0060076	excitatory synapse	Srpx2	IDA		Rat	PMID:24179158|RGD:8553698
Cellular Component	GO:0005615	extracellular space	SRPX2	IDA		Human	PMID:22242148
Cellular Component	GO:0005615	extracellular space	SRPX2	IDA		Human	PMID:9864177
Cellular Component	GO:0005615	extracellular space	Srpx2	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0097060	synaptic membrane	Srpx2	IDA		Rat	PMID:24179158|RGD:8553698
Biological Process	GO:0048870	cell motility	SRPX2	IDA		Human	PMID:19065654
Biological Process	GO:0098609	cell-cell adhesion	SRPX2	IDA		Human	PMID:19065654
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	Srpx2	IMP		Mouse	MGI:MGI:4412425|PMID:19667118
Biological Process	GO:0051965	positive regulation of synapse assembly	SRPX2	IDA		Human	PMID:24179158
Biological Process	GO:0051965	positive regulation of synapse assembly	Srpx2	IDA		Rat	PMID:24179158|RGD:8553698
Biological Process	GO:0042325	regulation of phosphorylation	SRPX2	IDA		Human	PMID:19065654
Biological Process	GO:0071625	vocalization behavior	Srpx2	IMP		Mouse	MGI:MGI:5527007|PMID:24179158

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern