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Srpx2 Gene Detail
Summary
  • Symbol
    Srpx2
  • Name
    sushi-repeat-containing protein, X-linked 2
  • Synonyms
    1110039C07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916042
    NCBI Gene: 68792
  • Gene Overview
    MyGene.info: SRPX2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:133908426-133932446 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 55.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916042
protein coding gene ChrX:133908416-133932448 (.)
129S1/SvImJ MGP_129S1SvImJ_G0036058
protein coding gene ChrX:131051567-131074329 (+)
A/J MGP_AJ_G0036040
protein coding gene ChrX:130481118-130503245 (+)
AKR/J MGP_AKRJ_G0035959
protein coding gene ChrX:134649526-134672428 (+)
BALB/cJ MGP_BALBcJ_G0036031
protein coding gene ChrX:128929381-128952620 (+)
C3H/HeJ MGP_C3HHeJ_G0035735
protein coding gene ChrX:131136636-131157548 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036553
protein coding gene ChrX:134917176-134941172 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033381
protein coding gene ChrX:122686097-122710528 (+)
CAST/EiJ MGP_CASTEiJ_G0035022
protein coding gene ChrX:112012691-112035716 (+)
CBA/J MGP_CBAJ_G0035712
protein coding gene ChrX:138955091-138977833 (+)
DBA/2J MGP_DBA2J_G0035865
protein coding gene ChrX:129822059-129844799 (+)
FVB/NJ MGP_FVBNJ_G0035807
protein coding gene ChrX:129134376-129156841 (+)
LP/J MGP_LPJ_G0035958
protein coding gene ChrX:131931335-131954071 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035835
protein coding gene ChrX:146352478-146375636 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036582
protein coding gene ChrX:130484713-130507571 (+)
PWK/PhJ MGP_PWKPhJ_G0034714
protein coding gene ChrX:108968293-108992618 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034546
protein coding gene ChrX:112638245-112662434 (+)
WSB/EiJ MGP_WSBEiJ_G0035159
protein coding gene ChrX:128865653-128892555 (+)



Homology
more
  • Human Ortholog
    SRPX2, sushi repeat containing protein X-linked 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SRPX2, sushi repeat containing protein X-linked 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BPP, CBPS, PMGX, RESDX, SRPUL
  • Links
    NCBI Gene ID: 27286
    neXtProt AC: NX_O60687
    UniProt: O60687

  • Chr Location
    Xq22.1; chrX:100644166-100671299 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8704
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SRPX2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit abnormal vocalization and response to social novelty.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031253 Ensembl Gene Model | MGI Sequence Detail 24021 C57BL/6J ±  kb
transcript ENSMUST00000033606 Ensembl | MGI Sequence Detail 2290 Not Applicable  
polypeptide ENSMUSP00000033606 Ensembl | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:262853 Soteros BM, et al., Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated gene. PLoS One. 2018;13(6):e0199399

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory