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Srpx2
Gene Detail
Symbol

Name
ID
Srpx2
sushi-repeat-containing protein, X-linked 2
MGI:1916042
Synonyms
1110039C07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome X
55.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:133908426-133932446 bp, + strand
From VEGA annotation of GRCm38

  24021 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SRPX2
Gene Tree: Srpx2

Human
homologs
SRPX2, sushi-repeat containing protein, X-linked 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 27286
neXtProt AC: NX_O60687

Human Synonyms: BPP, CBPS, PMGX, RESDX, SRPUL

Human Chr (Location): Xq22.1; chrX:100644166-100671299 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SRPX2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from CvDC )
Interactions
Srpx2 interacts with 148 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process angiogenesis, cell adhesion, ...
Component cell junction, cell surface, ...
Function hepatocyte growth factor binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (120)    Tissues (18)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 120
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase srpx2    NEW 
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000018714 (Evidence)
Ensembl Gene Model ENSMUSG00000031253 (Evidence)
Entrez Gene 68792 (Evidence)
UniGene 263553
DFCI TC1582796, TC1676224
DoTS DT.111028621, DT.40176515, DT.60105184
NIA Mouse Gene Index U020189
Consensus CDS Project CCDS41119.2
International Mouse Phenotyping Consortium Status Srpx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018714 VEGA Gene Model | MGI Sequence Detail 24021 C57BL/6J ±  kb
transcript OTTMUST00000045009 VEGA | MGI Sequence Detail 2290 Not Applicable 
polypeptide OTTMUSP00000020224 VEGA | MGI Sequence Detail 468 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025232 Domain of unknown function DUF4174
InterPro IPR003410 HYR domain
InterPro IPR028768 Sushi repeat-containing protein SRPX2
InterPro IPR000436 Sushi/SCR/CCP domain
Protein Ontology PR:000015635 sushi repeat-containing protein SRPX2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:222626 McClelland KS, et al., Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells. Biol Reprod. 2015 Jun;92(6):145
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory