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Srpx2 Gene Detail
Summary
  • Symbol
    Srpx2
  • Name
    sushi-repeat-containing protein, X-linked 2
  • Synonyms
    1110039C07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916042
    NCBI Gene: 68792
  • Gene Overview
    MyGene.info: SRPX2
Location & Maps
more
  • Sequence Map
    ChrX:133908426-133932446 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24021 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 55.47 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SRPX2, sushi repeat containing protein, X-linked 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SRPX2, sushi repeat containing protein, X-linked 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BPP, CBPS, PMGX, RESDX, SRPUL
  • Links
    NCBI Gene ID: 27286
    neXtProt AC: NX_O60687

  • Chr Location
    Xq22.1; chrX:100644166-100671299 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8704
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SRPX2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human SRPX2 associations

Human Disease Mouse Models
       Rolandic Epilepsy, Mental Retardation, and Speech Dyspraxia, X-Linked;   OMIM: 300643
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018714 VEGA Gene Model | MGI Sequence Detail 24021 C57BL/6J ±  kb
transcript OTTMUST00000045009 VEGA | MGI Sequence Detail 2290 Not Applicable  
polypeptide OTTMUSP00000020224 VEGA | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    135 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015635 sushi repeat-containing protein SRPX2
  • InterPro Domains
    IPR025232 Domain of unknown function DUF4174
    IPR003410 HYR domain
    IPR028768 Sushi repeat-containing protein SRPX2
    IPR000436 Sushi/SCR/CCP domain
Molecular
Reagents
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  • All nucleic 19
    cDNA 19

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:222626 McClelland KS, et al., Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells. Biol Reprod. 2015 Jun;92(6):145

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory