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Srpx2
Gene Detail
Symbol

Name
ID
Srpx2
sushi-repeat-containing protein, X-linked 2
MGI:1916042
Synonyms
1110039C07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome X
55.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:133908426-133932446 bp, + strand
From VEGA annotation of GRCm38

  24021 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8704  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Srpx2

Human
homologs
Human Homolog SRPX2, sushi-repeat containing protein, X-linked 2
NCBI Gene ID 27286
neXtProt AC  NX_O60687
Human Synonyms  BPP, CBPS, PMGX, RESDX, SRPUL
Human Chr (Location)  Xq21.33-q23; chrX:100644166-100671299 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SRPX2
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Interactions
Srpx2 interacts with 149 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process angiogenesis, cell adhesion, ...
Component cell junction, cell surface, ...
Function hepatocyte growth factor binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (120)    Tissues (18)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 120
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000018714 (Evidence)
Ensembl Gene ModelENSMUSG00000031253 (Evidence)
Entrez Gene68792 (Evidence)
UniGene263553
DFCITC1582796, TC1676224
DoTSDT.111028621, DT.40176515, DT.60105184
NIA Mouse Gene IndexU020189
Consensus CDS ProjectCCDS41119.2
International Mouse Knockout Project StatusSrpx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018714 VEGA Gene Model | MGI Sequence Detail 24021 C57BL/6J ±  kb
transcript OTTMUST00000045010 VEGA | MGI Sequence Detail 2848 Not Applicable 
polypeptide OTTMUSP00000020225 VEGA | MGI Sequence Detail 468 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025232 Domain of unknown function DUF4174
InterPro IPR003410 Hyalin
InterPro IPR000436 Sushi/SCR/CCP
Protein Ontology PR:000015635 sushi repeat-containing protein SRPX2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203418 Sia GM, et al., The human language-associated gene SRPX2 regulates synapse formation and vocalization in mice. Science. 2013 Nov 22;342(6161):987-91
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory