Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTBN5
  • Mouse genes Sptbn5
  • Rat genes Sptbn5
  • Zfish genes sptbn5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptbn5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Sptbn5	IDA		Mouse	PMID:18796539
Molecular Function	GO:0034452	dynactin binding	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0045505	dynein intermediate chain binding	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0042802	identical protein binding	SPTBN5	IPI	UniProtKB:Q9NRC6	Human	PMID:23704327
Molecular Function	GO:0019894	kinesin binding	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0032029	myosin tail binding	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0002046	opsin binding	Sptbn5	IDA		Mouse	PMID:23704327
Molecular Function	GO:0005515	protein binding	Sptbn5	IPI	PR:Q99NH7	Mouse	PMID:18796539
Molecular Function	GO:0005515	protein binding	Sptbn5	IPI	PR:O70318	Mouse	PMID:18796539
Molecular Function	GO:0005515	protein binding	Sptbn5	IPI	PR:P48193	Mouse	PMID:18796539
Molecular Function	GO:0043621	protein self-association	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0030507	spectrin binding	SPTBN5	IDA		Human	PMID:23704327
Molecular Function	GO:0030507	spectrin binding	Sptbn5	IPI	PR:P16546	Mouse	PMID:18796539
Cellular Component	GO:0045179	apical cortex	Sptbn5	IDA		Mouse	PMID:18796539
Cellular Component	GO:0030863	cortical cytoskeleton	Sptbn5	IDA		Mouse	PMID:18796539
Cellular Component	GO:0005737	cytoplasm	SPTBN5	IDA		Human	PMID:23704327
Cellular Component	GO:0005875	microtubule associated complex	Sptbn5	IDA		Mouse	PMID:23704327
Cellular Component	GO:0032391	photoreceptor connecting cilium	SPTBN5	IDA		Human	PMID:23704327
Cellular Component	GO:0097381	photoreceptor disc membrane	SPTBN5	IDA		Human	PMID:23704327
Biological Process	GO:0021782	glial cell development	sptbn5	IMP	ZFIN:ZDB-CRISPR-191008-7,ZFIN:ZDB-CRISPR-191008-8	Zfish	PMID:30924555
Biological Process	GO:0007030	Golgi organization	SPTBN5	IMP		Human	PMID:23704327
Biological Process	GO:0007041	lysosomal transport	SPTBN5	IMP		Human	PMID:23704327
Biological Process	GO:0060041	retina development in camera-type eye	sptbn5	IMP	ZFIN:ZDB-CRISPR-191008-7,ZFIN:ZDB-CRISPR-191008-8	Zfish	PMID:30924555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern