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Sptbn5 Gene Detail
Summary
  • Symbol
    Sptbn5
  • Name
    spectrin beta, non-erythrocytic 5
  • Synonyms
    EG640524, Spnb5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685200
    NCBI Gene: 640524
  • Gene Overview
    MyGene.info: SPTBN5
Location & Maps
more
  • Sequence Map
    Chr2:120046157-120085772 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39616 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.11 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SPTBN5, spectrin beta, non-erythrocytic 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SPTBN5, spectrin beta, non-erythrocytic 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BSPECV, HUBSPECV, HUSPECV
  • Links
    NCBI Gene ID: 51332
    neXtProt AC: NX_Q9NRC6

  • Chr Location
    15q21; chr15:41848146-41894077 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Sptbn5
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Literature Summary
  • Other Mouse Links
  • Other Vertebrate Links
    Xenbase sptbn5
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015286 VEGA Gene Model | MGI Sequence Detail 39616 C57BL/6J ±  kb
transcript OTTMUST00000036197 VEGA | MGI Sequence Detail 3625 Not Applicable  
polypeptide OTTMUSP00000016265 VEGA | MGI Sequence Detail 1209 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    428 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001589 Actinin-type actin-binding domain, conserved site
    IPR001715 Calponin homology domain
    IPR018159 Spectrin/alpha-actinin
    IPR002017 Spectrin repeat
Molecular
Reagents
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  • Microarray probesets 1
Other
Accession IDs
less
MGI:3645670
References
more
  • Summaries
    All 12
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:142574 Legendre K, et al., alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. J Cell Sci. 2008 Oct 15;121(Pt 20):3347-56
  • Latest
    J:199579 Papal S, et al., The giant spectrin betaV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum Mol Genet. 2013 Sep 15;22(18):3773-88

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory