Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPRY3
  • Mouse genes Spry3
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spry3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q63572	Human	PMID:17974561
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:P51784	Human	PMID:29293652
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:O14633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:O43593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:O60336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:P29972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:P62760	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5T5B0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5T754	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5T7P2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5T7P3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q8IUH5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q92504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9BXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9H2X0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9HC98-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9Y2K5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPRY3	IPI	UniProtKB:Q9Y4H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Spry3	IPI	UniProtKB:P49817	Mouse	MGI:MGI:3695236|PMID:16877379
Molecular Function	GO:0005515	protein binding	Spry3	IPI	PR:Q9QXV8	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry3	IPI	MGI:MGI:1345188	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry3	IPI	PR:Q9WTP2	Mouse	PMID:16339969
Molecular Function	GO:0005515	protein binding	Spry3	IPI	PR:Q9QXV9	Mouse	PMID:16339969
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spry3	IMP		Mouse	MGI:MGI:3695236|PMID:16877379
Biological Process	GO:0043409	negative regulation of MAPK cascade	SPRY3	IMP		Human	PMID:30878395
Biological Process	GO:0150013	negative regulation of neuron projection arborization	Spry3	IMP		Mouse	MGI:MGI:5693300|PMID:26089202

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern