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Spry3
Gene Detail
Symbol

Name
ID
Spry3
sprouty homolog 3 (Drosophila)
MGI:1345188
Synonyms
LOC236576, sprouty3
Feature Type
protein coding gene
Genetic Map
Chromosome Unknown
Vertebrate
homology
HomoloGene:4265  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: sprouty homolog protein

Human
homologs
Human Homolog SPRY3, sprouty homolog 3 (Drosophila)
NCBI Gene ID 10251
neXtProt AC  NX_O43610
Human Synonyms  HSPRY3, spry-3
Human Chr (Location)  XYq28 and Yq12
Interactions
Spry3 interacts with 76 markers (Mir17, Mir20b, Mir21a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (11)    Tissues (9)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
Northern blot 4
Western blot 3
RT-PCR 2
cDNA source data(9)
External Resources: Allen Institute   GENSAT   GEO  
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(1)
Other database
links
Entrez Gene236576 (Evidence)
UniGene297666
DFCITC1718405
DoTSDT.87045605
NIA Mouse Gene IndexU170664
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript NM_001030293 RefSeq | MGI Sequence Detail 4542 C57BL/6 
polypeptide NP_001025464 RefSeq | MGI Sequence Detail 288 C57BL/6 

For the selected sequences
All sequences(11) RefSeq(2) UniProt(2)
Protein-related
information
ResourceIDDescription
InterPro IPR007875 Sprouty
Protein Ontology PR:000015584 protein sprouty homolog 3
References
(Earliest) J:55241 Minowada G, et al., Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development. 1999 Oct;126(20):4465-75
(Latest) J:197120 Sharma B, et al., Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses. J Biol Chem. 2012 Dec 7;287(50):42352-60
All references(21)
Other
accession IDs
MGI:2685237

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory