Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPESP1
  • Mouse genes Spesp1
  • Rat genes Spesp1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spesp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Spesp1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0001669	acrosomal vesicle	Spesp1	IDA		Mouse	PMID:20375058
Cellular Component	GO:0005829	cytosol	SPESP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SPESP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SPESP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007340	acrosome reaction	Spesp1	IMP	MGI:MGI:4838302	Mouse	PMID:20375058
Biological Process	GO:0009566	fertilization	Spesp1	IDA		Mouse	MGI:MGI:5643961|PMID:25761597
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	Spesp1	IMP	MGI:MGI:4838302	Mouse	PMID:20375058
Biological Process	GO:0035036	sperm-egg recognition	Spesp1	IDA		Mouse	MGI:MGI:5643961|PMID:25761597

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern