Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPARCL1
  • Mouse genes Sparcl1
  • Rat genes Sparcl1
  • Zfish genes sparcl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sparcl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPARCL1	IPI	UniProtKB:Q99972	Human	PMID:20926826
Cellular Component	GO:0098965	extracellular matrix of synaptic cleft	Sparcl1	IDA		Rat	PMID:17151913|RGD:13702411
Cellular Component	GO:0005576	extracellular region	SPARCL1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	SPARCL1	HDA		Human	PMID:16502470
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	IMP		Mouse	PMID:26771491
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	IPI		Mouse	PMID:26771491
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	IDA		Mouse	PMID:26771491
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	IDA		Rat	PMID:17151913|RGD:13702411
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	EXP		Rat	PMID:21788491|RGD:13702385
Cellular Component	GO:0098978	glutamatergic synapse	Sparcl1	IDA		Rat	PMID:21788491|RGD:13702385
Cellular Component	GO:0045202	synapse	Sparcl1	IDA		Rat	PMID:1690015|RGD:1298897
Biological Process	GO:0050807	regulation of synapse organization	Sparcl1	EXP		Rat	PMID:21788491|RGD:13702385
Biological Process	GO:0050807	regulation of synapse organization	Sparcl1	IDA		Rat	PMID:21788491|RGD:13702385
Biological Process	GO:0099560	synaptic membrane adhesion	Sparcl1	IDA		Mouse	PMID:26771491
Biological Process	GO:0099560	synaptic membrane adhesion	Sparcl1	IMP		Mouse	PMID:26771491
Biological Process	GO:0099560	synaptic membrane adhesion	Sparcl1	IPI		Mouse	PMID:26771491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern