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Sparcl1 Gene Detail
Summary
  • Symbol
    Sparcl1
  • Name
    SPARC-like 1
  • Synonyms
    Ecm2, hevin, mast9, Sc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108110
    NCBI Gene: 13602
  • Gene Overview
    MyGene.info: SPARCL1
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:104079111-104113733 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 50.55 cM, cytoband E4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    313 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108110
protein coding gene Chr5:104079108-104114088 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029809
protein coding gene Chr5:105747475-105787125 (-)
A/J MGP_AJ_G0029773
protein coding gene Chr5:101769398-101805551 (-)
AKR/J MGP_AKRJ_G0029721
protein coding gene Chr5:105054659-105093671 (-)
BALB/cJ MGP_BALBcJ_G0029785
protein coding gene Chr5:102828614-102866662 (-)
C3H/HeJ MGP_C3HHeJ_G0029508
protein coding gene Chr5:105463798-105499570 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030240
protein coding gene Chr5:110073259-110118178 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027475
protein coding gene Chr5:96901892-96935744 (-)
CAST/EiJ MGP_CASTEiJ_G0028919
protein coding gene Chr5:104167181-104204780 (-)
CBA/J MGP_CBAJ_G0029478
protein coding gene Chr5:113902853-113943327 (-)
DBA/2J MGP_DBA2J_G0029622
protein coding gene Chr5:101957778-101995415 (-)
FVB/NJ MGP_FVBNJ_G0029581
protein coding gene Chr5:100751350-100787881 (-)
LP/J MGP_LPJ_G0029710
protein coding gene Chr5:106312876-106351277 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029610
protein coding gene Chr5:118835314-118871660 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030273
protein coding gene Chr5:104587675-104622169 (-)
PWK/PhJ MGP_PWKPhJ_G0028637
protein coding gene Chr5:100416342-100452636 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028472
protein coding gene Chr5:102244382-102277510 (-)
WSB/EiJ MGP_WSBEiJ_G0028997
protein coding gene Chr5:104967738-105005004 (-)



Homology
more
  • Human Ortholog
    SPARCL1, SPARC like 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPARCL1, SPARC like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MAST9, MAST 9, PIG33, SC1
  • Links
    NCBI Gene ID: 8404
    neXtProt AC: NX_Q14515
    UniProt: Q14515

  • Chr Location
    4q22.1; chr4:87473330-87529503 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    1 images
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal histology and survival.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029309 Ensembl Gene Model | MGI Sequence Detail 34623 C57BL/6J ±  kb
transcript ENSMUST00000031249 Ensembl | MGI Sequence Detail 2759 Not Applicable  
polypeptide ENSMUSP00000031249 Ensembl | MGI Sequence Detail 650 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 200
    Genomic 4
    cDNA 192
    Primer pair 4

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37147
References
more
  • Summaries
    All 67
    Developmental Gene Expression 16
    Gene Ontology 6
    Phenotypes 18
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:251180 Meissburger B, et al., Regulation of adipogenesis by paracrine factors from adipose stromal-vascular fraction - a link to fat depot-specific differences. Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1121-1131

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory