Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX7
  • Mouse genes Sox7
  • Rat genes Sox7
  • Zfish genes sox7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SOX7	IDA		Human	PMID:19108950
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox7	IDA		Mouse	PMID:15082719
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox7	IDA		Mouse	PMID:19515696
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Sox7	IDA		Mouse	PMID:15220343
Molecular Function	GO:0005515	protein binding	SOX7	IPI	UniProtKB:O76003	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX7	IPI	UniProtKB:Q8N9R8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SOX7	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SOX7	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox7	IDA		Mouse	PMID:10320775
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SOX7	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox7	IDA		Mouse	MGI:MGI:4887547|PMID:19328208
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox7	IDA		Mouse	PMID:19515696
Cellular Component	GO:0005737	cytoplasm	SOX7	IDA		Human	PMID:18819930
Cellular Component	GO:0005737	cytoplasm	Sox7	IDA		Mouse	PMID:10320775
Cellular Component	GO:0005634	nucleus	SOX7	IDA		Human	PMID:18682240
Cellular Component	GO:0005634	nucleus	SOX7	IDA		Human	PMID:19108950
Cellular Component	GO:0005634	nucleus	Sox7	IDA		Mouse	PMID:21146513
Cellular Component	GO:0005634	nucleus	Sox7	IDA		Mouse	PMID:10320775
Biological Process	GO:0060840	artery development	sox7	IGI	ZFIN:ZDB-MRPHLNO-060626-6,ZFIN:ZDB-MRPHLNO-081022-1,ZFIN:ZDB-MRPHLNO-081022-2	Zfish	PMID:23818617
Biological Process	GO:0001568	blood vessel development	sox7	IMP	ZFIN:ZDB-GENO-150818-2	Zfish	PMID:25834021
Biological Process	GO:0001568	blood vessel development	sox7	IGI	ZFIN:ZDB-GENE-000526-1	Zfish	PMID:25834021
Biological Process	GO:0001568	blood vessel development	sox7	IGI	ZFIN:ZDB-GENE-990415-67	Zfish	PMID:25834021
Biological Process	GO:0001568	blood vessel development	sox7	IGI	ZFIN:ZDB-GENE-080725-1	Zfish	PMID:25834021
Biological Process	GO:0001706	endoderm formation	SOX7	IDA		Human	PMID:18682240
Biological Process	GO:0008285	negative regulation of cell population proliferation	SOX7	IDA		Human	PMID:19108950
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SOX7	IDA		Human	PMID:19108950
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	SOX7	IDA		Human	PMID:19108950
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox7	IDA		Mouse	PMID:15220343
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox7	IDA		Mouse	PMID:19515696
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	SOX7	IDA		Human	PMID:19108950
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Sox7	IDA		Mouse	PMID:15082719
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-081022-3,ZFIN:ZDB-MRPHLNO-081022-4	Zfish	PMID:18094332
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-080811-1,ZFIN:ZDB-MRPHLNO-080811-3	Zfish	PMID:18377889
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-080811-2,ZFIN:ZDB-MRPHLNO-080811-4	Zfish	PMID:18377889
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-081022-1,ZFIN:ZDB-MRPHLNO-081022-2	Zfish	PMID:21726513
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-081022-1,ZFIN:ZDB-MRPHLNO-081022-2	Zfish	PMID:18094332
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-080725-1,ZFIN:ZDB-MRPHLNO-080725-2	Zfish	PMID:18032732
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-081022-1,ZFIN:ZDB-MRPHLNO-081022-2	Zfish	PMID:21730073
Biological Process	GO:0001570	vasculogenesis	sox7	IGI	ZFIN:ZDB-MRPHLNO-081022-5,ZFIN:ZDB-MRPHLNO-081022-6	Zfish	PMID:18094332

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern