Sox7
Gene Detail

Symbol Name ID

Sox7 SRY-box containing gene 7 MGI:98369

Feature Type

protein coding gene

Genetic Map

Chromosome 14

33.34 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:63943706-63950732 bp, + strand From NCBI annotation of GRCm38   7027 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7949  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sox7

Human homologs

Human Homolog		SOX7, SRY (sex determining region Y)-box 7
NCBI Gene ID		83595
neXtProt AC		NX_Q9BT81
Human Chr (Location)		8p22; chr8:10581278-10588022 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
Human Diseases Modeled Using Mouse Sox7 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	endoderm formation, negative regulation of cell proliferation, ...
Component	cytoplasm, nucleus
Function	DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (23 records)
Data Summary: Results (261)    Tissues (168)    Images (17)
Theiler Stages: 2, 3, 4, 5, 10, 11, 15, 17, 18, 20, 21, 23, 26, 28

Assay Type	Results
RNA in situ	150
RT-PCR	111

cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(20) Primer pair(4)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000063060 (Evidence)
Entrez Gene	20680 (Evidence)
UniGene	42162
DFCI	TC1579935, TC1594816
DoTS	DT.50315687, DT.55248834
NIA Mouse Gene Index	U015758
Consensus CDS Project	CCDS27206.1
International Mouse Knockout Project Status	Sox7

Sequences

Length	Strain/Species
genomic	20680	NCBI Gene Model | MGI Sequence Detail	7027	C57BL/6J
transcript	NM_011446	RefSeq | MGI Sequence Detail	3266	Not Specified
polypeptide	P40646	UniProt | EBI | MGI Sequence Detail	380	Not Applicable

All sequences(21) RefSeq(2) UniProt(3)

Protein-related information

Resource	ID	Description
InterPro	IPR009071	High mobility group, superfamily
InterPro	IPR021934	Sox C-terminal transactivation domain
Protein Ontology	PR:000015433	transcription factor SOX-7

Graphical View of Protein Domain Structure

References

(Earliest) J:1195 Denny P, et al., A conserved family of genes related to the testis determining gene, SRY. Nucleic Acids Res. 1992 Jun 11;20(11):2887
(Latest) J:191641 Oommen S, et al., Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. PLoS One. 2012;7(9):e43857
All references(54)

Other accession IDs

MGD-MRK-14508