Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX5
  • Mouse genes Sox5
  • Rat genes Sox5
  • Zfish genes sox5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Sox5	IDA		Rat	PMID:26150426|RGD:11526869
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox5	IDA		Mouse	PMID:17084361
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox5	IGI	MGI:MGI:98368	Mouse	PMID:9755172
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Sox5	IDA		Mouse	PMID:22344693
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:O15266	Human	PMID:21262861
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:P03410	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:G2XKQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:O43186	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:P25791	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:P86479	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q6PF18	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q92993	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q96A09	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q9HC52	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q9P0T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:O43186	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SOX5	IPI	UniProtKB:Q08117	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Sox5	IPI	PR:P20263	Mouse	PMID:22344693
Molecular Function	GO:0005515	protein binding	Sox5	IPI	PR:P40645	Mouse	PMID:17084361
Molecular Function	GO:0000976	transcription cis-regulatory region binding	SOX5	IDA		Human	PMID:26525805
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox5	IDA		Mouse	PMID:17084361
Cellular Component	GO:0005667	transcription regulator complex	Sox5	IDA		Mouse	PMID:22344693
Biological Process	GO:0055059	asymmetric neuroblast division	SOX5	IGI	UniProtKB:Q23045	Human	PMID:23946438
Biological Process	GO:0001502	cartilage condensation	Sox5	IMP		Mouse	MGI:MGI:2446758|PMID:11702786
Biological Process	GO:0001502	cartilage condensation	Sox5	IMP		Mouse	MGI:MGI:3037234|PMID:14993235
Biological Process	GO:0051216	cartilage development	Sox5	IDA		Mouse	MGI:MGI:6414706|PMID:15529345
Biological Process	GO:0051216	cartilage development	Sox5	IMP		Mouse	MGI:MGI:5780653|PMID:26150426
Biological Process	GO:0051216	cartilage development	Sox5	IGI	MGI:MGI:98368	Mouse	PMID:15634692
Biological Process	GO:0045165	cell fate commitment	Sox5	IGI	MGI:MGI:98368	Mouse	PMID:15634692
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	SOX5	IDA		Human	PMID:21401405
Biological Process	GO:0021953	central nervous system neuron differentiation	Sox5	IGI	MGI:MGI:1929913	Mouse	PMID:18215621
Biological Process	GO:0002062	chondrocyte differentiation	Sox5	IMP		Mouse	MGI:MGI:3037234|PMID:14993235
Biological Process	GO:0002062	chondrocyte differentiation	Sox5	IMP		Mouse	MGI:MGI:2446758|PMID:11702786
Biological Process	GO:0001701	in utero embryonic development	Sox5	IMP	MGI:MGI:2447147	Mouse	PMID:17084361
Biological Process	GO:0050935	iridophore differentiation	sox5	IGI	ZFIN:ZDB-GENO-190116-3,ZFIN:ZDB-GENO-980202-1565	Zfish	PMID:29621239
Biological Process	GO:0030318	melanocyte differentiation	sox5	IGI	ZFIN:ZDB-GENO-190116-3,ZFIN:ZDB-GENO-980202-1565	Zfish	PMID:29621239
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Sox5	IDA		Mouse	PMID:17084361
Biological Process	GO:0048709	oligodendrocyte differentiation	Sox5	IMP	MGI:MGI:2447147	Mouse	PMID:17084361
Biological Process	GO:0061036	positive regulation of cartilage development	SOX5	IDA		Human	PMID:21401405
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	SOX5	IDA		Human	PMID:21401405
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Sox5	IDA		Mouse	MGI:MGI:5285147|PMID:20940257
Biological Process	GO:2000741	positive regulation of mesenchymal stem cell differentiation	SOX5	IDA		Human	PMID:21401405
Biological Process	GO:0060164	regulation of timing of neuron differentiation	Sox5	IMP		Mouse	PMID:18215621
Biological Process	GO:0050936	xanthophore differentiation	sox5	IGI	ZFIN:ZDB-GENO-190116-3,ZFIN:ZDB-GENO-980202-1565	Zfish	PMID:29621239

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern