Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOSTDC1
  • Mouse genes Sostdc1
  • Rat genes Sostdc1
  • Zfish genes sostdc1a,sostdc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sostdc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036122	BMP binding	SOSTDC1	IDA		Human	PMID:15020244
Molecular Function	GO:0098821	BMP receptor activity	SOSTDC1	IDA		Human	PMID:15020244
Molecular Function	GO:0005515	protein binding	Sostdc1	IPI	PR:P21275	Mouse	PMID:14623234
Molecular Function	GO:0005515	protein binding	Sostdc1	IPI	PR:P21274	Mouse	PMID:14623234
Molecular Function	GO:0005515	protein binding	Sostdc1	IPI	PR:P23359	Mouse	PMID:14623234
Molecular Function	GO:0005515	protein binding	Sostdc1	IPI	PR:P20722	Mouse	PMID:14623234
Cellular Component	GO:0005615	extracellular space	SOSTDC1	IDA		Human	PMID:15020244
Cellular Component	GO:0005615	extracellular space	Sostdc1	IDA		Mouse	PMID:14623234
Biological Process	GO:0030509	BMP signaling pathway	Sostdc1	IDA		Mouse	PMID:16179481
Biological Process	GO:0030509	BMP signaling pathway	Sostdc1	IGI	MGI:MGI:88180	Mouse	PMID:16179481
Biological Process	GO:0060070	canonical Wnt signaling pathway	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0045165	cell fate commitment	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0072148	epithelial cell fate commitment	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0031069	hair follicle morphogenesis	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0060648	mammary gland bud morphogenesis	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	SOSTDC1	IDA		Human	PMID:15020244
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Sostdc1	IDA		Mouse	PMID:16179481
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Sostdc1	IDA		Mouse	PMID:14623234
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Sostdc1	IGI	MGI:MGI:88180	Mouse	PMID:16179481
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:0010454	negative regulation of cell fate commitment	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:22509524
Biological Process	GO:2000016	negative regulation of determination of dorsal identity	SOSTDC1	IDA		Human	PMID:15020244
Biological Process	GO:0045662	negative regulation of myoblast differentiation	SOSTDC1	IDA		Human	PMID:15020244
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	SOSTDC1	IDA		Human	PMID:15020244
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Sostdc1	IGI	MGI:MGI:88180	Mouse	PMID:16179481
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:16179481
Biological Process	GO:0007389	pattern specification process	Sostdc1	IMP	MGI:MGI:3604658	Mouse	PMID:16179481

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern