Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC9B2
  • Mouse genes Slc9b2
  • Rat genes Slc9b2
  • Zfish genes si:dkey-162b23.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc9b2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SLC9B2	IPI	UniProtKB:Q86UD5	Human	PMID:28071645
Molecular Function	GO:0010348	lithium:proton antiporter activity	SLC9B2	IMP		Human	PMID:18000046
Molecular Function	GO:0010348	lithium:proton antiporter activity	SLC9B2	IMP		Human	PMID:28154142
Molecular Function	GO:0005515	protein binding	SLC9B2	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0015385	sodium:proton antiporter activity	SLC9B2	IMP		Human	PMID:18000046
Molecular Function	GO:0015385	sodium:proton antiporter activity	SLC9B2	EXP		Human	PMID:28154142
Molecular Function	GO:0015385	sodium:proton antiporter activity	SLC9B2	IMP		Human	PMID:28154142
Cellular Component	GO:0016323	basolateral plasma membrane	Slc9b2	IDA		Mouse	MGI:MGI:4462789|PMID:20441802
Cellular Component	GO:0010008	endosome membrane	Slc9b2	IDA		Mouse	MGI:MGI:5492253|PMID:23720317
Cellular Component	GO:0031966	mitochondrial membrane	SLC9B2	IDA		Human	PMID:18508966
Cellular Component	GO:0005886	plasma membrane	SLC9B2	IDA		Human	PMID:18000046
Cellular Component	GO:0005886	plasma membrane	SLC9B2	IDA		Human	PMID:18508966
Cellular Component	GO:0005886	plasma membrane	Slc9b2	IDA		Mouse	MGI:MGI:4462789|PMID:20441802
Cellular Component	GO:0097228	sperm principal piece	Slc9b2	IMP		Mouse	MGI:MGI:5883195|PMID:27010853
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc9b2	IDA		Mouse	MGI:MGI:5492253|PMID:23720317
Biological Process	GO:0072583	clathrin-dependent endocytosis	Slc9b2	IDA		Mouse	MGI:MGI:5492253|PMID:23720317
Biological Process	GO:0030317	flagellated sperm motility	Slc9b2	IMP		Mouse	MGI:MGI:5883195|PMID:27010853
Biological Process	GO:2001206	positive regulation of osteoclast development	Slc9b2	IDA		Mouse	PMID:18269914
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Slc9b2	IDA		Mouse	MGI:MGI:5492253|PMID:23720317
Biological Process	GO:0006814	sodium ion transport	SLC9B2	IDA		Human	PMID:18508966

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern