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Term Detail
GO term:sodium:proton antiporter activity
Synonym: pH-dependent sodium:hydrogen antiporter activity
Synonym: pH-dependent sodium:proton antiporter activity
Synonym: sodium:hydrogen antiporter activity
Synonym: sodium/hydrogen antiporter activity
Synonym: sodium:hydrogen exchange activity
Synonym: sodium:hydrogen exchanger
GO id:GO:0015385
Definition:Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
Number of paths to term: 12

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-ametal ion transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-ahydrogen ion transmembrane transporter activity
                                                                                is-asolute:proton antiporter activity
                                                                                        is-amonovalent cation:proton antiporter activity
                                                                                                is-alithium:proton antiporter activity
                                                                                                is-apotassium:proton antiporter activity
                                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-acation:cation antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-asolute:proton antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-aactive transmembrane transporter activity
                                        is-asecondary active transmembrane transporter activity
                                                is-aantiporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-acation:cation antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-aactive transmembrane transporter activity
                                        is-asecondary active transmembrane transporter activity
                                                is-aantiporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-asolute:proton antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-ametal ion transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-ahydrogen ion transmembrane transporter activity
                                                                                is-asolute:proton antiporter activity
                                                                                        is-amonovalent cation:proton antiporter activity
                                                                                                is-alithium:proton antiporter activity
                                                                                                is-apotassium:proton antiporter activity
                                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-acation:cation antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-asolute:cation antiporter activity
                                                                is-asolute:proton antiporter activity
                                                                        is-amonovalent cation:proton antiporter activity
                                                                                is-alithium:proton antiporter activity
                                                                                is-apotassium:proton antiporter activity
                                                                                is-asodium:proton antiporter activity [GO:0015385] (8 genes, 12 annotations)
                                                                                        is-asodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory