Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC4A11
  • Mouse genes Slc4a11
  • Rat genes Slc4a11
  • Zfish genes slc4a11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc4a11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046715	active borate transmembrane transporter activity	SLC4A11	IDA		Human	PMID:15525507
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	SLC4A11	IDA		Human	PMID:15525507
Molecular Function	GO:0046983	protein dimerization activity	SLC4A11	IDA		Human	PMID:22072594
Molecular Function	GO:0015252	proton channel activity	SLC4A11	IDA		Human	PMID:15525507
Molecular Function	GO:0015078	proton transmembrane transporter activity	SLC4A11	IDA		Human	PMID:27581649
Molecular Function	GO:0005272	sodium channel activity	SLC4A11	IDA		Human	PMID:15525507
Molecular Function	GO:0005372	water transmembrane transporter activity	SLC4A11	IDA		Human	PMID:23813972
Molecular Function	GO:0005372	water transmembrane transporter activity	SLC4A11	IDA		Human	PMID:31273259
Cellular Component	GO:0016324	apical plasma membrane	SLC4A11	IDA		Human	PMID:17715183
Cellular Component	GO:0016323	basolateral plasma membrane	SLC4A11	IDA		Human	PMID:23813972
Cellular Component	GO:0016323	basolateral plasma membrane	SLC4A11	IDA		Human	PMID:17715183
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a11	IDA		Mouse	MGI:MGI:5517757|PMID:23813972
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a11	IDA		Rat	PMID:17715183|RGD:15090851
Cellular Component	GO:0005886	plasma membrane	Slc4a11	IDA		Rat	PMID:17715183|RGD:15090851
Cellular Component	GO:0012506	vesicle membrane	Slc4a11	IDA		Rat	PMID:17715183|RGD:15090851
Biological Process	GO:0015701	bicarbonate transport	SLC4A11	IDA		Human	PMID:15525507
Biological Process	GO:0046713	borate transport	SLC4A11	IDA		Human	PMID:15525507
Biological Process	GO:0071476	cellular hypotonic response	SLC4A11	IDA		Human	PMID:23813972
Biological Process	GO:0071476	cellular hypotonic response	SLC4A11	IDA		Human	PMID:31273259
Biological Process	GO:0034599	cellular response to oxidative stress	SLC4A11	IMP		Human	PMID:28642546
Biological Process	GO:0042044	fluid transport	Slc4a11	IMP		Mouse	MGI:MGI:4820694|PMID:20185830
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	SLC4A11	IDA		Human	PMID:15525507
Biological Process	GO:0050801	monoatomic ion homeostasis	Slc4a11	IMP		Mouse	MGI:MGI:4820694|PMID:20185830
Biological Process	GO:1902600	proton transmembrane transport	SLC4A11	IDA		Human	PMID:15525507
Biological Process	GO:2000739	regulation of mesenchymal stem cell differentiation	Slc4a11	IMP		Mouse	MGI:MGI:6695689|PMID:33247189
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	SLC4A11	IMP		Human	PMID:28642546
Biological Process	GO:0006814	sodium ion transport	SLC4A11	IDA		Human	PMID:15525507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern