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Term Detail
GO term:sodium channel activity
GO id:GO:0005272
Definition:Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
Number of paths to term: 11

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-ametal ion transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                                        is-aligand-gated sodium channel activity +
                                                                                        is-avoltage-gated sodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity +
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                                        is-aligand-gated sodium channel activity +
                                                                                        is-avoltage-gated sodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity +
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-acation channel activity
                                                                        is-aacetylcholine-activated cation-selective channel activity
                                                                        is-aammonium channel activity
                                                                        is-acalcium activated cation channel activity +
                                                                        is-acalcium channel activity +
                                                                        is-aextracellular ATP-gated cation channel activity
                                                                        is-ahydrogen ion channel activity +
                                                                        is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                        is-amethylammonium channel activity
                                                                        is-apotassium channel activity +
                                                                        is-aserotonin-activated cation-selective channel activity
                                                                        is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                                is-aligand-gated sodium channel activity +
                                                                                is-avoltage-gated sodium channel activity +
                                                                        is-atemperature-gated cation channel activity
                                                                        is-avoltage-gated cation channel activity +
                                                                        is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-ametal ion transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                                        is-aligand-gated sodium channel activity +
                                                                                        is-avoltage-gated sodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity +
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-ainorganic cation transmembrane transporter activity
                                                                is-amonovalent inorganic cation transmembrane transporter activity
                                                                        is-asodium ion transmembrane transporter activity
                                                                                is-acalcium, potassium:sodium antiporter activity
                                                                                is-acalcium:sodium antiporter activity +
                                                                                is-amelibiose:sodium symporter activity
                                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                                        is-aligand-gated sodium channel activity +
                                                                                        is-avoltage-gated sodium channel activity +
                                                                                is-asodium ion uniporter activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-asodium-transporting ATP synthase activity, rotational mechanism
                                                                                is-asodium-transporting ATPase activity, rotational mechanism
                                                                                is-asodium:bicarbonate symporter activity
                                                                                is-asodium:phosphate symporter activity +
                                                                                is-asodium:potassium-exchanging ATPase activity +
                                                                                is-asodium:proton antiporter activity +
                                                                                is-asodium:sulfate symporter activity
                                                                                is-asolute:sodium symporter activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity [GO:0005272] (32 genes, 87 annotations)
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-avoltage-gated sodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory