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Comparative GO Graph (mouse, human, rat)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc18a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc18a1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0019899enzyme bindingSlc18a1IPIRGD:3853RatPMID:19903816|RGD:5128868
Molecular FunctionGO:0015311monoamine:proton antiporter activitySLC18A1IDAHumanPMID:8643547
Molecular FunctionGO:0015311monoamine:proton antiporter activitySlc18a1IDAMouseMGI:MGI:7413162|PMID:21712771
Molecular FunctionGO:0015311monoamine:proton antiporter activitySlc18a1IDARatPMID:8125935|RGD:155663520
Molecular FunctionGO:0005335serotonin:sodium:chloride symporter activitySlc18a1IDARatPMID:16926160|RGD:5130998
Cellular ComponentGO:0005737cytoplasmSlc18a1IDARatPMID:16926160|RGD:5130998
Cellular ComponentGO:0045202synapseSlc18a1IDAMousePMID:23201251
Biological ProcessGO:0071285cellular response to lithium ionSlc18a1IEPRatPMID:11080216|RGD:5131196
Biological ProcessGO:0051612negative regulation of serotonin uptakeSlc18a1IMPRatPMID:16926160|RGD:5130998
Biological ProcessGO:0033603positive regulation of dopamine secretionSlc18a1IMPRatPMID:17244889|RGD:5131195
Biological ProcessGO:0051610serotonin uptakeSLC18A1IDAHumanPMID:8643547
Biological ProcessGO:0051610serotonin uptakeSlc18a1IDAMouseMGI:MGI:7413162|PMID:21712771
Biological ProcessGO:0051610serotonin uptakeSlc18a1IDARatPMID:19008227|RGD:5131091
Biological ProcessGO:0051610serotonin uptakeSlc18a1IDARatPMID:8125935|RGD:155663520

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory