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Gene Ontology Browser
Term Detail
GO term:serotonin uptake
Synonym: 5-HT uptake
Synonym: 5HT uptake
Synonym: 5-hydroxytryptamine uptake
Synonym: serotonin import
GO id:GO:0051610
Definition:The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
Number of paths to term: 18

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of neurotransmitter levels
                                        is-aneurotransmitter uptake
                                                is-aacetylcholine uptake +
                                                is-aamino acid uptake involved in synaptic transmission +
                                                is-acatecholamine uptake involved in synaptic transmission +
                                                is-ahistamine uptake +
                                                negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                positively-regulatespositive regulation of neurotransmitter uptake +
                                                regulatesregulation of neurotransmitter uptake +
                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                        positively-regulatespositive regulation of serotonin uptake
                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of neurotransmitter levels
                                                                is-aneurotransmitter uptake
                                                                        is-aacetylcholine uptake +
                                                                        is-aamino acid uptake involved in synaptic transmission +
                                                                        is-acatecholamine uptake involved in synaptic transmission +
                                                                        is-ahistamine uptake +
                                                                        negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                                        positively-regulatespositive regulation of neurotransmitter uptake +
                                                                        regulatesregulation of neurotransmitter uptake +
                                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                                positively-regulatespositive regulation of serotonin uptake
                                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-anitrogen compound transport
                                        is-amonoamine transport
                                                is-aserotonin transport
                                                        is-aserotonin secretion +
                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                positively-regulatespositive regulation of serotonin uptake
                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-aorganic substance transport
                                        is-amonoamine transport
                                                is-aserotonin transport
                                                        is-aserotonin secretion +
                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                positively-regulatespositive regulation of serotonin uptake
                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-aion transport
                                                is-acation transport
                                                        is-aserotonin transport
                                                                is-aserotonin secretion +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-amonoamine transport
                                                is-aserotonin transport
                                                        is-aserotonin secretion +
                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                positively-regulatespositive regulation of serotonin uptake
                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-aestablishment of localization
                        is-atransport
                                is-asingle-organism transport
                                        is-aneurotransmitter transport
                                                is-aneurotransmitter uptake
                                                        is-aacetylcholine uptake +
                                                        is-aamino acid uptake involved in synaptic transmission +
                                                        is-acatecholamine uptake involved in synaptic transmission +
                                                        is-ahistamine uptake +
                                                        negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                        positively-regulatespositive regulation of neurotransmitter uptake +
                                                        regulatesregulation of neurotransmitter uptake +
                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                positively-regulatespositive regulation of serotonin uptake
                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-anitrogen compound transport
                                                is-amonoamine transport
                                                        is-aserotonin transport
                                                                is-aserotonin secretion +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-amonoamine transport
                                                        is-aserotonin transport
                                                                is-aserotonin secretion +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-aion transport
                                                        is-acation transport
                                                                is-aserotonin transport
                                                                        is-aserotonin secretion +
                                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                                positively-regulatespositive regulation of serotonin uptake
                                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-amonoamine transport
                                                        is-aserotonin transport
                                                                is-aserotonin secretion +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        part-ofestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-aneurotransmitter transport
                                                        is-aneurotransmitter uptake
                                                                is-aacetylcholine uptake +
                                                                is-aamino acid uptake involved in synaptic transmission +
                                                                is-acatecholamine uptake involved in synaptic transmission +
                                                                is-ahistamine uptake +
                                                                negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                                positively-regulatespositive regulation of neurotransmitter uptake +
                                                                regulatesregulation of neurotransmitter uptake +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of neurotransmitter levels
                                                        is-aneurotransmitter uptake
                                                                is-aacetylcholine uptake +
                                                                is-aamino acid uptake involved in synaptic transmission +
                                                                is-acatecholamine uptake involved in synaptic transmission +
                                                                is-ahistamine uptake +
                                                                negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                                positively-regulatespositive regulation of neurotransmitter uptake +
                                                                regulatesregulation of neurotransmitter uptake +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of neurotransmitter levels
                                                        is-aneurotransmitter uptake
                                                                is-aacetylcholine uptake +
                                                                is-aamino acid uptake involved in synaptic transmission +
                                                                is-acatecholamine uptake involved in synaptic transmission +
                                                                is-ahistamine uptake +
                                                                negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                                positively-regulatespositive regulation of neurotransmitter uptake +
                                                                regulatesregulation of neurotransmitter uptake +
                                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                                        positively-regulatespositive regulation of serotonin uptake
                                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of neurotransmitter levels
                                                                is-aneurotransmitter uptake
                                                                        is-aacetylcholine uptake +
                                                                        is-aamino acid uptake involved in synaptic transmission +
                                                                        is-acatecholamine uptake involved in synaptic transmission +
                                                                        is-ahistamine uptake +
                                                                        negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                                        positively-regulatespositive regulation of neurotransmitter uptake +
                                                                        regulatesregulation of neurotransmitter uptake +
                                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                                positively-regulatespositive regulation of serotonin uptake
                                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-aion transport
                                        is-acation transport
                                                is-aserotonin transport
                                                        is-aserotonin secretion +
                                                        is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                                negatively-regulatesnegative regulation of serotonin uptake +
                                                                positively-regulatespositive regulation of serotonin uptake
                                                                regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-amonoamine transport
                                        is-aserotonin transport
                                                is-aserotonin secretion +
                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                        positively-regulatespositive regulation of serotonin uptake
                                                        regulatesregulation of serotonin uptake +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-aneurotransmitter transport
                                        is-aneurotransmitter uptake
                                                is-aacetylcholine uptake +
                                                is-aamino acid uptake involved in synaptic transmission +
                                                is-acatecholamine uptake involved in synaptic transmission +
                                                is-ahistamine uptake +
                                                negatively-regulatesnegative regulation of neurotransmitter uptake +
                                                positively-regulatespositive regulation of neurotransmitter uptake +
                                                regulatesregulation of neurotransmitter uptake +
                                                is-aserotonin uptake [GO:0051610] (5 genes, 8 annotations)
                                                        negatively-regulatesnegative regulation of serotonin uptake +
                                                        positively-regulatespositive regulation of serotonin uptake
                                                        regulatesregulation of serotonin uptake +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory