Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SIRPB1,SIRPG
  • Mouse genes Sirpb1a
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sirpb1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SIRPB1	IPI	UniProtKB:O43914	Human	PMID:10940905
Molecular Function	GO:0005515	protein binding	SIRPG	IPI	UniProtKB:Q08722	Human	PMID:15383453
Molecular Function	GO:0005515	protein binding	SIRPG	IPI	UniProtKB:P01100	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SIRPG	IPI	UniProtKB:P50440	Human	PMID:32814053
Cellular Component	GO:0016020	membrane	SIRPG	IDA		Human	PMID:15383453
Cellular Component	GO:0005886	plasma membrane	Sirpb1a	IDA		Mouse	PMID:15123631
Biological Process	GO:0051649	establishment of localization in cell	Sirpb1a	IDA		Mouse	PMID:15123631
Biological Process	GO:0035556	intracellular signal transduction	Sirpb1a	IDA		Mouse	PMID:15123631
Biological Process	GO:0006909	phagocytosis	Sirpb1a	IDA		Mouse	PMID:15123631
Biological Process	GO:0008284	positive regulation of cell population proliferation	SIRPG	IDA		Human	PMID:15383453
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	SIRPG	IDA		Human	PMID:15383453
Biological Process	GO:0050766	positive regulation of phagocytosis	Sirpb1a	IDA		Mouse	PMID:15123631
Biological Process	GO:0050870	positive regulation of T cell activation	SIRPG	IDA		Human	PMID:15383453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern