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Sirpb1a Gene Detail
Summary
  • Symbol
    Sirpb1a
  • Name
    signal-regulatory protein beta 1A
  • Synonyms
    9930027N05Rik, Sirpb1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444824
    NCBI Gene: 320832
  • Gene Overview
    MyGene.info: SIRPB1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:15371661-15426522 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 3.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    592 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444824
protein coding gene Chr3:15371653-15426522 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0026796
protein coding gene Chr3:13024616-13061141 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027499
protein coding gene Chr3:13476728-13570929 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024861
protein coding gene Chr3:11040181-11090242 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026772
protein coding gene Chr3:13751523-13850859 (-)
DBA/2J MGP_DBA2J_G0026907
protein coding gene Chr3:12055447-12117613 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0027018
protein coding gene Chr3:13175918-13355180 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026897
protein coding gene Chr3:15516118-15562299 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025791
protein coding gene Chr3:12383768-12621120 (-)
WSB/EiJ MGP_WSBEiJ_G0026325
protein coding gene Chr3:12521630-12560179 (-)



Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
    Orthology source: HomoloGene
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8
    UniProt: O00241, Q5TFQ8

  • Chr Location
    20p13; chr20:1564193-1620457 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320832 NCBI Gene Model | MGI Sequence Detail 54862 C57BL/6J ±  kb
transcript NM_001002898 RefSeq | MGI Sequence Detail 1232 C57BL/6  
polypeptide NP_001002898 RefSeq | MGI Sequence Detail 391 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 6

    Microarray probesets 5
References
more
  • Summaries
    All 20
    Diseases 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:190315 Rousseaux MW, et al., Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15918-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory