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Sirpb1a Gene Detail
Summary
  • Symbol
    Sirpb1a
  • Name
    signal-regulatory protein beta 1A
  • Synonyms
    9930027N05Rik, Sirpb1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444824
    NCBI Gene: 320832
  • Gene Overview
    MyGene.info: SIRPB1
Location & Maps
more
  • Sequence Map
    Chr3:15371653-15426520 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      54868 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 3.59 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8

  • Chr Location
    20p13; chr20:1564383-1626497 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Radiation induced
    1
  • Genomic Mutations
    1 involving Sirpb1a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052297 VEGA Gene Model | MGI Sequence Detail 54868 C57BL/6J ±  kb
transcript OTTMUST00000131321 VEGA | MGI Sequence Detail 1419 Not Applicable  
polypeptide OTTMUSP00000070245 VEGA | MGI Sequence Detail 397 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    592 from dbSNP Build 142
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 5
References
more
  • Summaries
    All 17
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:190315 Rousseaux MW, et al., Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15918-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory