Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHROOM3
  • Mouse genes Shroom3
  • Rat genes Shroom3
  • Zfish genes shroom3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shroom3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Shroom3	IDA		Mouse	PMID:10589677
Cellular Component	GO:0005912	adherens junction	Shroom3	IDA		Mouse	PMID:10589677
Cellular Component	GO:0043296	apical junction complex	Shroom3	IDA		Mouse	PMID:16249236
Cellular Component	GO:0045177	apical part of cell	Shroom3	IDA		Mouse	PMID:16249236
Cellular Component	GO:0016324	apical plasma membrane	Shroom3	IDA		Mouse	PMID:15037549
Cellular Component	GO:0005856	cytoskeleton	Shroom3	IDA		Mouse	PMID:10589677
Biological Process	GO:0030036	actin cytoskeleton organization	Shroom3	IGI	MGI:MGI:107926	Mouse	PMID:16249236
Biological Process	GO:0030036	actin cytoskeleton organization	Shroom3	IGI	MGI:MGI:1930780	Mouse	PMID:16249236
Biological Process	GO:0030036	actin cytoskeleton organization	Shroom3	IGI	MGI:MGI:107927	Mouse	PMID:16249236
Biological Process	GO:0002066	columnar/cuboidal epithelial cell development	Shroom3	IDA		Mouse	PMID:16249236
Biological Process	GO:0001843	neural tube closure	Shroom3	IMP	MGI:MGI:1889778	Mouse	PMID:16249236
Biological Process	GO:0007389	pattern specification process	Shroom3	IMP	MGI:MGI:1889778	Mouse	PMID:10589677
Biological Process	GO:0072015	podocyte development	shroom3	IMP	ZFIN:ZDB-MRPHLNO-150331-1	Zfish	PMID:25273069
Biological Process	GO:0048919	posterior lateral line neuromast development	shroom3	IMP		Zfish	PMID:23136387
Biological Process	GO:0008360	regulation of cell shape	Shroom3	IDA		Mouse	PMID:16249236

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern