Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3BP5
  • Mouse genes Sh3bp5
  • Rat genes Sh3bp5
  • Zfish genes sh3bp5a,sh3bp5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3bp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	SH3BP5	IDA		Human	PMID:26506309
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	SH3BP5	IDA		Human	PMID:30217979
Molecular Function	GO:0005515	protein binding	SH3BP5	IPI	UniProtKB:P62491	Human	PMID:30217979
Molecular Function	GO:0005515	protein binding	SH3BP5	IPI	UniProtKB:Q8IY31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3BP5	IPI	UniProtKB:Q9ULW6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3BP5	IPI	UniProtKB:Q06187	Human	PMID:9571151
Molecular Function	GO:0005515	protein binding	Sh3bp5	IPI	UniProtKB:P45984	Rat	PMID:15158451|RGD:8554456
Molecular Function	GO:0005515	protein binding	Sh3bp5	IPI	UniProtKB:P53778	Rat	PMID:15158451|RGD:8554456
Molecular Function	GO:0004860	protein kinase inhibitor activity	SH3BP5	IDA		Human	PMID:10339589
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	SH3BP5	IDA		Human	PMID:30217979
Cellular Component	GO:0005739	mitochondrion	Sh3bp5	IDA		Rat	PMID:12167088|RGD:737651
Cellular Component	GO:0005739	mitochondrion	Sh3bp5	IDA		Rat	PMID:15158451|RGD:8554456
Cellular Component	GO:0016604	nuclear body	SH3BP5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SH3BP5	IDA		Human	GO_REF:0000052
Biological Process	GO:0035556	intracellular signal transduction	SH3BP5	IDA		Human	PMID:10339589
Biological Process	GO:0006469	negative regulation of protein kinase activity	Sh3bp5	IDA		Mouse	MGI:MGI:1337389|PMID:10339589

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern