Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SGPP1
  • Mouse genes Sgpp1
  • Rat genes Sgpp1
  • Zfish genes sgpp1a,sgpp1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sgpp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	SGPP1	IDA		Human	PMID:16782891
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Sgpp1	IDA		Mouse	PMID:10859351
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Sgpp1	IDA		Mouse	PMID:12235122
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Sgpp1	IDA		Mouse	PMID:11756451
Cellular Component	GO:0005783	endoplasmic reticulum	Sgpp1	IDA		Mouse	PMID:12235122
Cellular Component	GO:0016020	membrane	Sgpp1	IDA		Mouse	PMID:10859351
Cellular Component	GO:0016020	membrane	Sgpp1	IDA		Mouse	PMID:11756451
Biological Process	GO:0035621	ER to Golgi ceramide transport	SGPP1	IMP		Human	PMID:16782891
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Sgpp1	IDA		Mouse	PMID:12235122
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Sgpp1	IDA		Mouse	PMID:10859351
Biological Process	GO:0045682	regulation of epidermis development	Sgpp1	IMP		Mouse	MGI:MGI:5503267|PMID:23637227
Biological Process	GO:0045616	regulation of keratinocyte differentiation	Sgpp1	IMP		Mouse	MGI:MGI:5503267|PMID:23637227
Biological Process	GO:0006668	sphinganine-1-phosphate metabolic process	Sgpp1	IDA		Mouse	PMID:11756451
Biological Process	GO:0006668	sphinganine-1-phosphate metabolic process	Sgpp1	IDA		Mouse	PMID:10859351
Biological Process	GO:0006665	sphingolipid metabolic process	Sgpp1	IDA		Mouse	PMID:10859351
Biological Process	GO:0006665	sphingolipid metabolic process	Sgpp1	IDA		Mouse	PMID:12235122
Biological Process	GO:0006670	sphingosine metabolic process	Sgpp1	IDA		Mouse	PMID:11756451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern