Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD3
  • Mouse genes Setd3
  • Rat genes Setd3
  • Zfish genes setd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	Setd3	IDA		Mouse	PMID:21832073
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	setd3	IDA		Zfish	PMID:21307598
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	Setd3	IDA		Mouse	PMID:21832073
Molecular Function	GO:0005515	protein binding	SETD3	IPI	UniProtKB:P12004	Human	PMID:26030842
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	SETD3	IDA		Human	PMID:30526847
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	SETD3	IDA		Human	PMID:30626964
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	SETD3	IDA		Human	PMID:30785395
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	SETD3	IDA		Human	PMID:31388018
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	SETD3	IDA		Human	PMID:31993215
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	Setd3	IMP		Mouse	MGI:MGI:6276231|PMID:30626964
Molecular Function	GO:0018064	protein-L-histidine N-tele-methyltransferase activity	Setd3	IDA		Rat	PMID:30526847|RGD:13838798
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Setd3	IPI	PR:P10085	Mouse	PMID:21832073
Molecular Function	GO:0003713	transcription coactivator activity	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Cellular Component	GO:0000785	chromatin	Setd3	IDA		Mouse	PMID:21832073
Cellular Component	GO:0005737	cytoplasm	SETD3	IDA		Human	PMID:30626964
Biological Process	GO:0030047	actin modification	SETD3	IDA		Human	PMID:30526847
Biological Process	GO:0030047	actin modification	SETD3	IDA		Human	PMID:30626964
Biological Process	GO:0030047	actin modification	SETD3	IDA		Human	PMID:30785395
Biological Process	GO:0030047	actin modification	SETD3	IDA		Human	PMID:31388018
Biological Process	GO:0030047	actin modification	SETD3	IDA		Human	PMID:31993215
Biological Process	GO:0030047	actin modification	Setd3	IMP		Mouse	MGI:MGI:6276231|PMID:30626964
Biological Process	GO:0030047	actin modification	Setd3	IDA		Rat	PMID:30526847|RGD:13838798
Biological Process	GO:0016570	histone modification	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0018021	peptidyl-histidine methylation	SETD3	IDA		Human	PMID:30526847
Biological Process	GO:0018021	peptidyl-histidine methylation	SETD3	IDA		Human	PMID:30626964
Biological Process	GO:0018021	peptidyl-histidine methylation	SETD3	IDA		Human	PMID:30785395
Biological Process	GO:0018021	peptidyl-histidine methylation	SETD3	IDA		Human	PMID:31388018
Biological Process	GO:0018021	peptidyl-histidine methylation	SETD3	IDA		Human	PMID:31993215
Biological Process	GO:0018021	peptidyl-histidine methylation	Setd3	IMP		Mouse	MGI:MGI:6276231|PMID:30626964
Biological Process	GO:0018021	peptidyl-histidine methylation	Setd3	IDA		Rat	PMID:30526847|RGD:13838798
Biological Process	GO:0018027	peptidyl-lysine dimethylation	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0018026	peptidyl-lysine monomethylation	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0018023	peptidyl-lysine trimethylation	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	Setd3	IMP		Mouse	PMID:21832073
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Setd3	IGI	MGI:MGI:97275	Mouse	PMID:21832073
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Setd3	IDA		Mouse	PMID:21832073
Biological Process	GO:0006479	protein methylation	setd3	IDA		Zfish	PMID:21307598|ZFIN:ZDB-PUB-110214-28
Biological Process	GO:0070472	regulation of uterine smooth muscle contraction	Setd3	IMP		Mouse	MGI:MGI:6276231|PMID:30626964

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern