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Gene Ontology Browser
Term Detail
GO term:histone methyltransferase activity (H3-K4 specific)
Synonym: histone H3 lysine 4-specific methyltransferase activity
Synonym: histone lysine N-methyltransferase activity (H3-K4 specific)
Synonym: histone methylase activity (H3-K4 specific)
GO id:GO:0042800
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein.
CommentsNote that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aN-methyltransferase activity
                                                        is-alysine N-methyltransferase activity
                                                                is-aprotein-lysine N-methyltransferase activity
                                                                        is-ahistone-lysine N-methyltransferase activity
                                                                                is-ahistone methyltransferase activity (H3-K27 specific)
                                                                                is-ahistone methyltransferase activity (H3-K36 specific)
                                                                                is-ahistone methyltransferase activity (H3-K4 specific) [GO:0042800] (12 genes, 13 annotations)
                                                                                is-ahistone methyltransferase activity (H3-K79 specific)
                                                                                is-ahistone methyltransferase activity (H3-K9 specific)
                                                                                is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aprotein methyltransferase activity
                                                        is-ahistone methyltransferase activity
                                                                is-ahistone-lysine N-methyltransferase activity
                                                                        is-ahistone methyltransferase activity (H3-K27 specific)
                                                                        is-ahistone methyltransferase activity (H3-K36 specific)
                                                                        is-ahistone methyltransferase activity (H3-K4 specific) [GO:0042800] (12 genes, 13 annotations)
                                                                        is-ahistone methyltransferase activity (H3-K79 specific)
                                                                        is-ahistone methyltransferase activity (H3-K9 specific)
                                                                        is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aprotein methyltransferase activity
                                                        is-aprotein-lysine N-methyltransferase activity
                                                                is-ahistone-lysine N-methyltransferase activity
                                                                        is-ahistone methyltransferase activity (H3-K27 specific)
                                                                        is-ahistone methyltransferase activity (H3-K36 specific)
                                                                        is-ahistone methyltransferase activity (H3-K4 specific) [GO:0042800] (12 genes, 13 annotations)
                                                                        is-ahistone methyltransferase activity (H3-K79 specific)
                                                                        is-ahistone methyltransferase activity (H3-K9 specific)
                                                                        is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aS-adenosylmethionine-dependent methyltransferase activity
                                                        is-alysine N-methyltransferase activity
                                                                is-aprotein-lysine N-methyltransferase activity
                                                                        is-ahistone-lysine N-methyltransferase activity
                                                                                is-ahistone methyltransferase activity (H3-K27 specific)
                                                                                is-ahistone methyltransferase activity (H3-K36 specific)
                                                                                is-ahistone methyltransferase activity (H3-K4 specific) [GO:0042800] (12 genes, 13 annotations)
                                                                                is-ahistone methyltransferase activity (H3-K79 specific)
                                                                                is-ahistone methyltransferase activity (H3-K9 specific)
                                                                                is-ahistone methyltransferase activity (H4-K20 specific)


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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory