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Setd3 Gene Detail
Summary
  • Symbol
    Setd3
  • Name
    SET domain containing 3
  • Synonyms
    2610102I01Rik, 2610305M23Rik, D12Ertd771e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289184
    NCBI Gene: 52690
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:108106431-108179314 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 59.23 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    565 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289184
protein coding gene Chr12:108106431-108179462 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020100
protein coding gene Chr12:110169653-110261438 (-)
A/J MGP_AJ_G0020054
protein coding gene Chr12:106037101-106108927 (-)
AKR/J MGP_AKRJ_G0020030
protein coding gene Chr12:109101541-109176474 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0019842
protein coding gene Chr12:109542915-109617549 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020485
protein coding gene Chr12:113572038-113650643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018097
protein coding gene Chr12:102568052-102642611 (-)
CAST/EiJ MGP_CASTEiJ_G0019384
protein coding gene Chr12:104460925-104538801 (-)
CBA/J MGP_CBAJ_G0019809
protein coding gene Chr12:118083596-118159673 (-)
DBA/2J MGP_DBA2J_G0019926
protein coding gene Chr12:105552622-105631695 (-)
FVB/NJ MGP_FVBNJ_G0019911
protein coding gene Chr12:104334671-104409923 (-)
LP/J MGP_LPJ_G0020001
protein coding gene Chr12:110054017-110140252 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019949
protein coding gene Chr12:121287350-121387742 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020514
protein coding gene Chr12:108553385-108632491 (-)
PWK/PhJ MGP_PWKPhJ_G0019143
protein coding gene Chr12:100167855-100241632 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018947
protein coding gene Chr12:102769469-102846566 (-)
WSB/EiJ MGP_WSBEiJ_G0019441
protein coding gene Chr12:109510513-109576188 (-)



Homology
more
  • Human Ortholog
    SETD3, SET domain containing 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SETD3, SET domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf154
  • Links
    NCBI Gene ID: 84193
    neXtProt AC: NX_Q86TU7
    UniProt: Q86TU7

  • Chr Location
    14q32.2; chr14:99397746-99486458 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41748
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SETD3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056770 Ensembl Gene Model | MGI Sequence Detail 72884 C57BL/6J ±  kb
transcript ENSMUST00000071095 Ensembl | MGI Sequence Detail 2755 Not Applicable  
polypeptide ENSMUSP00000066413 Ensembl | MGI Sequence Detail 594 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1919723, MGI:1919763
References
more
  • Summaries
    All 32
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory