Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINI1
  • Mouse genes Serpini1
  • Rat genes Serpini1
  • Zfish genes serpini1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpini1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPINI1	IDA		Human	PMID:19285087
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPINI1	IDA		Human	PMID:9442076
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	Serpini1	IDA		Rat	PMID:12438159|RGD:633912
Cellular Component	GO:0060205	cytoplasmic vesicle lumen	SERPINI1	IDA		Human	PMID:17040209
Cellular Component	GO:0070062	extracellular exosome	SERPINI1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	SERPINI1	IDA		Human	PMID:17040209
Cellular Component	GO:0005615	extracellular space	Serpini1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0043025	neuronal cell body	SERPINI1	IDA		Human	PMID:17040209
Cellular Component	GO:0043025	neuronal cell body	Serpini1	IDA		Mouse	MGI:MGI:3699790|PMID:17040209
Cellular Component	GO:0034774	secretory granule lumen	Serpini1	IDA		Mouse	MGI:MGI:3699790|PMID:17040209
Biological Process	GO:0010976	positive regulation of neuron projection development	Serpini1	IDA		Rat	PMID:23825416|RGD:8655547
Biological Process	GO:0030155	regulation of cell adhesion	Serpini1	IDA		Rat	PMID:12438159|RGD:633912
Biological Process	GO:0010975	regulation of neuron projection development	serpini1	IMP	ZFIN:ZDB-GENO-221027-4	Zfish	PMID:33168193
Biological Process	GO:0006979	response to oxidative stress	serpini1	IMP	ZDB:ZDB-GENO-221110-1	Zfish	PMID:33737878
Biological Process	GO:0001966	thigmotaxis	serpini1	IMP	ZFIN:ZDB-GENO-221027-1	Zfish	PMID:33168193

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern