Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINB6
  • Mouse genes Serpinb6b
  • Rat genes Serpinb6b
  • Zfish genes serpinb14,serpinb1l1,serpinb1l4,zgc:173729
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpinb6b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002020	protease binding	SERPINB6	IPI	UniProtKB:P20231	Human	PMID:14670919
Molecular Function	GO:0002020	protease binding	SERPINB6	IPI	UniProtKB:O60259	Human	PMID:17761692
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	SERPINB6	IDA		Human	PMID:17761692
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINB6	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINB6	HDA		Human	PMID:28675934
Cellular Component	GO:0005737	cytoplasm	SERPINB6	IDA		Human	PMID:14670919
Cellular Component	GO:0005737	cytoplasm	SERPINB6	IDA		Human	PMID:17761692
Cellular Component	GO:0005737	cytoplasm	SERPINB6	IDA		Human	PMID:20451170
Cellular Component	GO:0005737	cytoplasm	Serpinb6b	IDA		Mouse	MGI:MGI:5582855|PMID:24505135
Cellular Component	GO:0070062	extracellular exosome	SERPINB6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SERPINB6	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	SERPINB6	HDA		Human	PMID:27068509
Cellular Component	GO:0005634	nucleus	Serpinb6b	IDA		Mouse	MGI:MGI:5582855|PMID:24505135
Cellular Component	GO:0097180	serine protease inhibitor complex	SERPINB6	IDA		Human	PMID:17761692
Biological Process	GO:0071470	cellular response to osmotic stress	SERPINB6	IMP		Human	PMID:20451170
Biological Process	GO:0010951	negative regulation of endopeptidase activity	SERPINB6	IDA		Human	PMID:17761692
Biological Process	GO:0007605	sensory perception of sound	SERPINB6	IMP		Human	PMID:20451170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern