Serpinb6b
Gene Detail

Symbol Name ID

Serpinb6b serine (or cysteine) peptidase inhibitor, clade B, member 6b MGI:894688

Synonyms

NK13, ovalbumin, Spi12

Feature Type

protein coding gene

Genetic Map

Chromosome 13

13.78 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr13:32965209-32979067 bp, + strand From VEGA annotation of GRCm38   13859 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22633  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpinb6b

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	gonad development, negative regulation of endopeptidase activity, ...
Component	intracellular
Function	serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (105)    Tissues (23)    Images (24)
Theiler Stages: 18, 23, 28

Assay Type	Results
RNA in situ	98
RT-PCR	7

cDNA source data(39)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(45) Genomic(2) cDNA(39) Primer pair(3) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000000698 (Evidence)
Ensembl Gene Model	ENSMUSG00000042842 (Evidence)
Entrez Gene	20708 (Evidence)
UniGene	36526
DFCI	TC1580589, TC1642087
DoTS	DT.110975521, DT.91447895
NIA Mouse Gene Index	U014708
Consensus CDS Project	CCDS26430.1
International Mouse Knockout Project Status	Serpinb6b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000000698	VEGA Gene Model | MGI Sequence Detail	13859	C57BL/6J
transcript	OTTMUST00000001331	VEGA | MGI Sequence Detail	2193	Not Applicable
polypeptide	OTTMUSP00000000628	VEGA | MGI Sequence Detail	377	Not Applicable

All sequences(31) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(45 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family

References

(Earliest) J:41085 Sun J, et al., A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9). J Biol Chem. 1997 Jun 13;272(24):15434-41
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)