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Serpinb6b Gene Detail
Summary
  • Symbol
    Serpinb6b
  • Name
    serine (or cysteine) peptidase inhibitor, clade B, member 6b
  • Synonyms
    NK13, ovalbumin, Spi12
  • Feature Type
    protein coding gene
  • IDs
    MGI:894688
    NCBI Gene: 20708
Location & Maps
more
  • Sequence Map
    Chr13:32965209-32979067 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13859 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 13.78 cM, cytoband A4
  • Mapping Data
    4 experiments
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Serpinb6b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000698 VEGA Gene Model | MGI Sequence Detail 13859 C57BL/6J ±  kb
transcript OTTMUST00000001331 VEGA | MGI Sequence Detail 2193 Not Applicable  
polypeptide OTTMUSP00000000628 VEGA | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    95 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    Genomic 2
    cDNA 39
    Primer pair 3
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:41085 Sun J, et al., A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9). J Biol Chem. 1997 Jun 13;272(24):15434-41
  • Latest
    J:213076 Kaiserman D, et al., Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A. J Biol Chem. 2014 Mar 28;289(13):9408-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory