Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINA3
  • Mouse genes Serpina3k
  • Rat genes Serpina3c,Serpina3l,Serpina3m
  • Zfish genes serpina1,serpina1l,serpina7,si:ch211-186e20.7,zgc:113828,zgc:174259,zgc:174260
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpina3k

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q92876	Human	PMID:12709365
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q96KC8	Human	PMID:14668352
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UKR3	Human	PMID:14687906
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q96AX1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SERPINA3	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Serpina3k	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0072562	blood microparticle	SERPINA3	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINA3	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINA3	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Serpina3k	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Serpina3k	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	SERPINA3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SERPINA3	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	SERPINA3	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	SERPINA3	IDA		Human	PMID:25645918
Biological Process	GO:0016525	negative regulation of angiogenesis	Serpina3c	IMP		Rat	PMID:12743698|RGD:1580111
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	Serpina3c	IMP		Rat	PMID:12743698|RGD:1580111
Biological Process	GO:0043065	positive regulation of apoptotic process	Serpina3c	IDA		Rat	PMID:12743698|RGD:1580111
Biological Process	GO:0034097	response to cytokine	Serpina3k	IDA		Mouse	PMID:15795238
Biological Process	GO:0043434	response to peptide hormone	Serpina3k	IDA		Mouse	PMID:15795238

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern