Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCTR
  • Mouse genes Sctr
  • Rat genes Sctr
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sctr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042277	peptide binding	Sctr	IPI	RGD:3643	Rat	PMID:12403838|RGD:9590237
Molecular Function	GO:0042277	peptide binding	Sctr	IDA		Rat	PMID:1646711|RGD:729676
Molecular Function	GO:0017046	peptide hormone binding	SCTR	IPI	UniProtKB:P09683	Human	PMID:7612008
Molecular Function	GO:0015055	secretin receptor activity	SCTR	IDA		Human	PMID:7612008
Molecular Function	GO:0015055	secretin receptor activity	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Molecular Function	GO:0015055	secretin receptor activity	Sctr	IDA		Rat	PMID:1646711|RGD:729676
Cellular Component	GO:0005881	cytoplasmic microtubule	SCTR	IDA		Human	PMID:23264731
Biological Process	GO:0007420	brain development	Sctr	IEP		Rat	PMID:15276242|RGD:9590241
Biological Process	GO:0002024	diet induced thermogenesis	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	SCTR	IDA		Human	PMID:7612008
Biological Process	GO:0009992	intracellular water homeostasis	Sctr	IMP		Mouse	MGI:MGI:3709930|PMID:17283064
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Sctr	IDA		Rat	PMID:12403838|RGD:9590237
Biological Process	GO:0050996	positive regulation of lipid catabolic process	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0050996	positive regulation of lipid catabolic process	Sctr	IMP		Mouse	MGI:MGI:5562611|PMID:24273196
Biological Process	GO:0032098	regulation of appetite	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0032098	regulation of appetite	Sctr	IMP		Mouse	MGI:MGI:6294194|PMID:20927047
Biological Process	GO:0048167	regulation of synaptic plasticity	Sctr	IMP		Mouse	MGI:MGI:3690260|PMID:17008357
Biological Process	GO:0070295	renal water absorption	Sctr	IMP		Mouse	MGI:MGI:3709930|PMID:17283064
Biological Process	GO:0031667	response to nutrient levels	Sctr	IDA		Mouse	MGI:MGI:6259360|PMID:30449620

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern