Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAV1
  • Mouse genes Sav1
  • Rat genes Sav1
  • Zfish genes sav1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sav1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SAV1	IPI	UniProtKB:Q9H4B6	Human	PMID:16930133
Molecular Function	GO:0042802	identical protein binding	SAV1	IPI	UniProtKB:Q9H4B6	Human	PMID:17517604
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:16930133
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:16930133
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043-1	Human	PMID:17517604
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:A6NIX2	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q96IF1	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:O00165	Human	PMID:21567072
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:O00165	Human	PMID:22570112
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:23386615
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13043	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:28087714
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAV1	IPI	UniProtKB:Q13188	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Sav1	IPI	PR:P37238	Mouse	PMID:22292086
Cellular Component	GO:0005737	cytoplasm	SAV1	IDA		Human	PMID:19212654
Cellular Component	GO:0005829	cytosol	SAV1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SAV1	IDA		Human	PMID:19212654
Biological Process	GO:0060038	cardiac muscle cell proliferation	Sav1	IMP	MGI:MGI:2654594,MGI:MGI:4430538	Mouse	PMID:21512031
Biological Process	GO:0060271	cilium assembly	sav1	IMP	ZFIN:ZDB-MRPHLNO-170914-4	Zfish	PMID:25367221
Biological Process	GO:0050673	epithelial cell proliferation	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0001942	hair follicle development	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0035329	hippo signaling	Sav1	IMP		Mouse	MGI:MGI:4420842|PMID:20080689
Biological Process	GO:0035329	hippo signaling	Sav1	IMP	MGI:MGI:2654594,MGI:MGI:4430538	Mouse	PMID:21512031
Biological Process	GO:0035329	hippo signaling	Sav1	IGI	MGI:MGI:103262	Mouse	PMID:18369314
Biological Process	GO:0035329	hippo signaling	Sav1	IGI	MGI:MGI:1354386	Mouse	PMID:18369314
Biological Process	GO:0035329	hippo signaling	Sav1	IGI	MGI:MGI:1929004	Mouse	PMID:18369314
Biological Process	GO:0035329	hippo signaling	Sav1	IGI	MGI:MGI:1333883	Mouse	PMID:18369314
Biological Process	GO:0060575	intestinal epithelial cell differentiation	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0097283	keratinocyte apoptotic process	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0030216	keratinocyte differentiation	Sav1	IGI	MGI:MGI:1929004	Mouse	PMID:18369314
Biological Process	GO:0030216	keratinocyte differentiation	Sav1	IGI	MGI:MGI:1333883	Mouse	PMID:18369314
Biological Process	GO:0030216	keratinocyte differentiation	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0030216	keratinocyte differentiation	Sav1	IGI	MGI:MGI:1354386	Mouse	PMID:18369314
Biological Process	GO:0030216	keratinocyte differentiation	Sav1	IGI	MGI:MGI:103262	Mouse	PMID:18369314
Biological Process	GO:0060487	lung epithelial cell differentiation	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	Sav1	IMP	MGI:MGI:2654594,MGI:MGI:4430538	Mouse	PMID:21512031
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Sav1	IGI	MGI:MGI:1928487	Mouse	PMID:22292086
Biological Process	GO:1902174	positive regulation of keratinocyte apoptotic process	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0046620	regulation of organ growth	Sav1	IMP	MGI:MGI:2654594,MGI:MGI:4430538	Mouse	PMID:21512031
Biological Process	GO:2000036	regulation of stem cell population maintenance	Sav1	IMP	MGI:MGI:3790763	Mouse	PMID:18369314
Biological Process	GO:0060412	ventricular septum morphogenesis	Sav1	IMP	MGI:MGI:2654594,MGI:MGI:4430538	Mouse	PMID:21512031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern