Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SATB1
  • Mouse genes Satb1
  • Rat genes Satb1
  • Zfish genes satb1a,satb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Satb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Satb1	IDA		Mouse	PMID:21930775
Molecular Function	GO:0003677	DNA binding	Satb1	IDA		Mouse	PMID:15851481
Molecular Function	GO:0003677	DNA binding	Satb1	IDA		Mouse	PMID:8114718
Molecular Function	GO:0003677	DNA binding	Satb1	IDA		Mouse	PMID:12692553
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Satb1	IDA		Mouse	PMID:12692553
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Satb1	IPI	UniProtKB:P17433	Mouse	MGI:MGI:6284428|PMID:29924977
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SATB1	IDA		Human	PMID:15851481
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:P55212	Human	PMID:18408014
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:P63165	Human	PMID:18408014
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:P35222	Human	PMID:20126258
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:G2XKQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SATB1	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SATB1	IDA		Human	PMID:15851481
Molecular Function	GO:0043565	sequence-specific DNA binding	SATB1	IDA		Human	PMID:15851481
Cellular Component	GO:0000785	chromatin	Satb1	IDA		Mouse	PMID:15851481
Cellular Component	GO:0000792	heterochromatin	Satb1	IDA		Mouse	PMID:12692553
Cellular Component	GO:0016604	nuclear body	SATB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	SATB1	IDA		Human	PMID:33513338
Cellular Component	GO:0016363	nuclear matrix	Satb1	IDA		Mouse	PMID:15851481
Cellular Component	GO:0005654	nucleoplasm	SATB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SATB1	IDA		Human	PMID:18408014
Cellular Component	GO:0016605	PML body	SATB1	IDA		Human	PMID:18408014
Biological Process	GO:0050798	activated T cell proliferation	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:15814699
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:10716941
Biological Process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:15814699
Biological Process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:10716941
Biological Process	GO:0006325	chromatin organization	Satb1	IDA		Mouse	PMID:12692553
Biological Process	GO:0006338	chromatin remodeling	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:21930775
Biological Process	GO:0008544	epidermis development	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:21930775
Biological Process	GO:0030099	myeloid cell differentiation	satb1b	IMP	ZFIN:ZDB-MRPHLNO-141013-32	Zfish	PMID:25010335
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SATB1	IMP		Human	PMID:15851481
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SATB1	IDA		Human	PMID:15851481
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SATB1	IDA		Human	PMID:33513338
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Satb1	IDA		Mouse	PMID:15851481
Biological Process	GO:0030223	neutrophil differentiation	satb1b	IMP	ZFIN:ZDB-MRPHLNO-141013-32	Zfish	PMID:25010335
Biological Process	GO:0060004	reflex	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:10716941
Biological Process	GO:0006355	regulation of DNA-templated transcription	Satb1	IMP		Mouse	MGI:MGI:6284428|PMID:29924977
Biological Process	GO:0006355	regulation of DNA-templated transcription	Satb1	IDA		Mouse	PMID:12692553
Biological Process	GO:0042110	T cell activation	Satb1	IMP	MGI:MGI:2386676	Mouse	PMID:10716941

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern