Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRAS
  • Mouse genes Rras
  • Rat genes Rras
  • Zfish genes rras
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rras

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RRAS	IDA		Human	PMID:16773572
Molecular Function	GO:0019003	GDP binding	RRAS	IMP		Human	PMID:24705357
Molecular Function	GO:0003924	GTPase activity	RRAS	IDA		Human	PMID:16773572
Molecular Function	GO:0003924	GTPase activity	RRAS	IMP		Human	PMID:24705357
Molecular Function	GO:0005515	protein binding	RRAS	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	RRAS	IPI	UniProtKB:O43157	Human	PMID:19843518
Molecular Function	GO:0005515	protein binding	RRAS	IPI	UniProtKB:P52306-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rras	IPI	UniProtKB:O08773	Rat	PMID:19319189|RGD:8554645
Molecular Function	GO:0044877	protein-containing complex binding	RRAS	IDA		Human	PMID:23209302
Cellular Component	GO:0070062	extracellular exosome	RRAS	HDA		Human	PMID:19056867
Cellular Component	GO:0005925	focal adhesion	RRAS	HDA		Human	PMID:21423176
Biological Process	GO:0016477	cell migration	Rras	IGI	MGI:MGI:97306	Mouse	PMID:14724565
Biological Process	GO:0060325	face morphogenesis	RRAS	IMP		Human	PMID:24705357
Biological Process	GO:0002521	leukocyte differentiation	RRAS	IMP		Human	PMID:24705357
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	rras	IMP	ZFIN:ZDB-MRPHLNO-110223-5	Zfish	PMID:21262462
Biological Process	GO:1900148	negative regulation of Schwann cell migration	Rras	IGI	MGI:MGI:97306	Mouse	PMID:14724565
Biological Process	GO:0007219	Notch signaling pathway	rras	IMP	ZFIN:ZDB-MRPHLNO-110223-5	Zfish	PMID:21262462
Biological Process	GO:0045766	positive regulation of angiogenesis	RRAS	IMP		Human	PMID:21393242
Biological Process	GO:0010595	positive regulation of endothelial cell migration	RRAS	IMP		Human	PMID:22825554
Biological Process	GO:1904906	positive regulation of endothelial cell-matrix adhesion via fibronectin	RRAS	IMP		Human	PMID:22825554
Biological Process	GO:2001214	positive regulation of vasculogenesis	RRAS	IMP		Human	PMID:22825554
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	RRAS	IMP		Human	PMID:24705357
Biological Process	GO:0051896	regulation of protein kinase B signaling	RRAS	IMP		Human	PMID:24705357
Biological Process	GO:0036135	Schwann cell migration	Rras	IGI	MGI:MGI:97306	Mouse	PMID:14724565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern