Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPL23
  • Mouse genes Rpl23
  • Rat genes Rpl23
  • Zfish genes rpl23
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpl23

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:P46777,UniProtKB:P62913,UniProtKB:Q00987	Human	PMID:15314173
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q9P287	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q00987	Human	PMID:17110929
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q00987	Human	PMID:17310983
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q9P287	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL23	IPI	UniProtKB:Q9P287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rpl23	IPI	UniProtKB:P23804	Mouse	MGI:MGI:4830897|PMID:20832751
Molecular Function	GO:0003723	RNA binding	RPL23	HDA		Human	PMID:22658674
Molecular Function	GO:0003735	structural constituent of ribosome	RPL23	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPL23	IDA		Human	PMID:32669547
Molecular Function	GO:0003735	structural constituent of ribosome	Rpl23	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Molecular Function	GO:0001223	transcription coactivator binding	RPL23	IPI	UniProtKB:P06748	Human	PMID:19160485
Molecular Function	GO:1990948	ubiquitin ligase inhibitor activity	RPL23	IDA		Human	PMID:15314173
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RPL23	IPI	UniProtKB:Q00987	Human	PMID:15314173
Cellular Component	GO:0005737	cytoplasm	RPL23	IDA		Human	PMID:15314173
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL23	IPI		Human	PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL23	HDA		Human	PMID:12962325
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL23	IDA		Human	PMID:32669547
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl23	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl23	IPI		Mouse	MGI:MGI:6810796|PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl23	IDA		Rat	PMID:7451403|RGD:11036084
Cellular Component	GO:0022626	cytosolic ribosome	RPL23	IDA		Human	PMID:23636399
Cellular Component	GO:0070062	extracellular exosome	RPL23	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	RPL23	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	RPL23	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	RPL23	IDA		Human	PMID:15314173
Cellular Component	GO:0005730	nucleolus	RPL23	IDA		Human	PMID:19160485
Cellular Component	GO:0005730	nucleolus	Rpl23	IDA		Mouse	PMID:11809816
Cellular Component	GO:0005654	nucleoplasm	RPL23	IDA		Human	PMID:15314173
Cellular Component	GO:0014069	postsynaptic density	Rpl23	EXP		Rat	PMID:16507876|RGD:13702274
Cellular Component	GO:0014069	postsynaptic density	Rpl23	IDA		Rat	PMID:16507876|RGD:13702274
Cellular Component	GO:0032991	protein-containing complex	RPL23	IMP		Human	PMID:15314173
Cellular Component	GO:0032991	protein-containing complex	RPL23	IDA		Human	PMID:19160485
Cellular Component	GO:0005840	ribosome	Rpl23	IDA		Rat	PMID:3730400|RGD:11036081
Cellular Component	GO:0045202	synapse	Rpl23	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Rpl23	EXP		Mouse	PMID:25211037
Biological Process	GO:0072717	cellular response to actinomycin D	RPL23	IMP		Human	PMID:15314173
Biological Process	GO:0070314	G1 to G0 transition	RPL23	IMP		Human	PMID:19160485
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	RPL23	IMP		Human	PMID:19160485
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	RPL23	IDA		Human	PMID:15314173
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	RPL23	IDA		Human	PMID:15314173
Biological Process	GO:0008284	positive regulation of cell population proliferation	RPL23	IMP		Human	PMID:19160485
Biological Process	GO:0010628	positive regulation of gene expression	RPL23	IMP		Human	PMID:15314173
Biological Process	GO:1901798	positive regulation of signal transduction by p53 class mediator	RPL23	IMP		Human	PMID:15314173
Biological Process	GO:0050821	protein stabilization	RPL23	IMP		Human	PMID:15314173
Biological Process	GO:0050821	protein stabilization	RPL23	IMP		Human	PMID:19160485
Biological Process	GO:0032986	protein-DNA complex disassembly	RPL23	IDA		Human	PMID:19160485
Biological Process	GO:1903450	regulation of G1 to G0 transition	RPL23	IMP		Human	PMID:15314173

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern