Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPE,RPEL1
  • Mouse genes Rpe
  • Rat genes Rpe
  • Zfish genes rpe
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	Rpe	IDA		Rat	PMID:2843500|RGD:1599574
Molecular Function	GO:0004750	D-ribulose-phosphate 3-epimerase activity	RPE	IDA		Human	PMID:20923965
Molecular Function	GO:0004750	D-ribulose-phosphate 3-epimerase activity	Rpe	IDA		Mouse	PMID:5360673
Molecular Function	GO:0004750	D-ribulose-phosphate 3-epimerase activity	Rpe	IDA		Rat	PMID:2843500|RGD:1599574
Molecular Function	GO:0004750	D-ribulose-phosphate 3-epimerase activity	Rpe	IDA		Rat	PMID:3079759|RGD:1641816
Molecular Function	GO:0042802	identical protein binding	RPE	IPI	UniProtKB:Q96AT9	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	RPE	IPI	UniProtKB:Q96AT9	Human	PMID:20923965
Molecular Function	GO:0042802	identical protein binding	RPE	IPI	UniProtKB:Q96AT9	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RPE	IPI	UniProtKB:Q96AT9	Human	PMID:32296183
Molecular Function	GO:0046872	metal ion binding	RPE	IDA		Human	PMID:20923965
Molecular Function	GO:0048029	monosaccharide binding	Rpe	IDA		Rat	PMID:3079759|RGD:1641816
Molecular Function	GO:0005515	protein binding	RPE	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	RPE	IPI	UniProtKB:Q96AT9	Human	PMID:20923965
Cellular Component	GO:0005829	cytosol	Rpe	IDA		Mouse	PMID:5360673
Cellular Component	GO:0070062	extracellular exosome	RPE	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Rpe	IDA		Rat	PMID:2843500|RGD:1599574
Biological Process	GO:0005975	carbohydrate metabolic process	RPE	IDA		Human	PMID:20923965
Biological Process	GO:0060271	cilium assembly	rpe	IMP	ZFIN:ZDB-MRPHLNO-170127-9	Zfish	PMID:27903883
Biological Process	GO:0060271	cilium assembly	rpe	IMP	ZFIN:ZDB-MRPHLNO-170127-10	Zfish	PMID:27903883
Biological Process	GO:0006098	pentose-phosphate shunt	RPE	IDA		Human	PMID:20923965
Biological Process	GO:0006098	pentose-phosphate shunt	Rpe	IDA		Mouse	PMID:5360673
Biological Process	GO:0006098	pentose-phosphate shunt	Rpe	IDA		Rat	PMID:2843500|RGD:1599574
Biological Process	GO:0009052	pentose-phosphate shunt, non-oxidative branch	Rpe	IDA		Rat	PMID:3079759|RGD:1641816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern