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Rpe Gene Detail
Summary
  • Symbol
    Rpe
  • Name
    ribulose-5-phosphate-3-epimerase
  • Synonyms
    2810429B02Rik, 5730518J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913896
    NCBI Gene: 66646
  • Gene Overview
    MyGene.info: RPE
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:66700831-66719805 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 33.61 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    171 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913896
protein coding gene Chr1:66700812-66719805 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016114
protein coding gene Chr1:66962778-66981785 (+)
A/J MGP_AJ_G0016097
protein coding gene Chr1:64592442-64611038 (+)
AKR/J MGP_AKRJ_G0016054
protein coding gene Chr1:66438281-66456932 (+)
BALB/cJ MGP_BALBcJ_G0016052
protein coding gene Chr1:64666896-64685071 (+)
C3H/HeJ MGP_C3HHeJ_G0015883
protein coding gene Chr1:66688985-66707881 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016505
protein coding gene Chr1:69547283-69565032 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014226
protein coding gene Chr1:60528072-60545041 (+)
CAST/EiJ MGP_CASTEiJ_G0015467
protein coding gene Chr1:65923982-65944018 (+)
CBA/J MGP_CBAJ_G0015856
protein coding gene Chr1:71791239-71815749 (+)
DBA/2J MGP_DBA2J_G0015957
protein coding gene Chr1:63983103-64001541 (+)
FVB/NJ MGP_FVBNJ_G0015960
protein coding gene Chr1:63235922-63253496 (+)
LP/J MGP_LPJ_G0016029
protein coding gene Chr1:67905168-67926466 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015980
protein coding gene Chr1:74761320-74793599 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016552
protein coding gene Chr1:66390946-66411071 (+)
PWK/PhJ MGP_PWKPhJ_G0015254
protein coding gene Chr1:63377227-63396323 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015033
protein coding gene Chr1:65852718-65870127 (+)
WSB/EiJ MGP_WSBEiJ_G0015529
protein coding gene Chr1:66117452-66135400 (+)



Homology
more
  • Human Ortholog
    RPE, ribulose-5-phosphate-3-epimerase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RPE, ribulose-5-phosphate-3-epimerase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RPE2-1
  • Links
    NCBI Gene ID: 6120
    neXtProt AC: NX_Q96AT9
    UniProt: Q96AT9

  • Chr Location
    2q34; chr2:210002565-210029156 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12005
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RPE
  • Protein SuperFamily
    RPE
  • Gene Tree
    Rpe
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Rpe
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026005 Ensembl Gene Model | MGI Sequence Detail 18975 C57BL/6J ±  kb
transcript ENSMUST00000113995 Ensembl | MGI Sequence Detail 2713 Not Applicable  
polypeptide ENSMUSP00000109628 Ensembl | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920011
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory