MGI 5.13 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	pentose-phosphate shunt
Synonym:	hexose monophosphate pathway
Synonym:	pentose phosphate pathway
Synonym:	pentose-phosphate pathway
Synonym:	pentose phosphate shunt
GO id:	GO:0006098
Definition:	The process in which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
Number of paths to term:	38

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

biological_process

cellular process

cellular metabolic process

cellular aromatic compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

cellular nitrogen compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

cellular nitrogen compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

cofactor metabolic process

coenzyme metabolic process

oxidoreduction coenzyme metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

heterocycle metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

heterocycle metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

phosphorus metabolic process

organophosphate metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

cellular process

cellular metabolic process

phosphorus metabolic process

phosphate-containing compound metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

catabolic process

organic substance catabolic process

carbohydrate catabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

cellular aromatic compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

cellular nitrogen compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

cellular nitrogen compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

cofactor metabolic process

coenzyme metabolic process

oxidoreduction coenzyme metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

heterocycle metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

heterocycle metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

phosphorus metabolic process

organophosphate metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

cellular metabolic process

phosphorus metabolic process

phosphate-containing compound metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

nitrogen compound metabolic process

cellular nitrogen compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

nitrogen compound metabolic process

cellular nitrogen compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

nitrogen compound metabolic process

organonitrogen compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

carbohydrate metabolic process

carbohydrate catabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

hexose metabolic process

glucose metabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

hexose metabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic substance catabolic process

carbohydrate catabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organonitrogen compound metabolic process

pyridine-containing compound metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organophosphate metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

primary metabolic process

carbohydrate metabolic process

carbohydrate catabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

primary metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

hexose metabolic process

glucose metabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

primary metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

hexose metabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

primary metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

monosaccharide metabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

primary metabolic process

carbohydrate metabolic process

single-organism carbohydrate metabolic process

single-organism carbohydrate catabolic process

monosaccharide catabolic process

hexose catabolic process

glucose catabolic process

glucose catabolic process to butanediol

glucose catabolic process to butyrate

glucose catabolic process to ethanol +

glucose catabolic process to lactate +

glycolysis +

non-phosphorylated glucose catabolic process

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

Gene_Ontology

biological_process

metabolic process

primary metabolic process

nucleobase-containing compound metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

oxidation-reduction process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

small molecule metabolic process

nucleobase-containing small molecule metabolic process

nucleoside phosphate metabolic process

nucleotide metabolic process

pyridine nucleotide metabolic process

nicotinamide nucleotide metabolic process

NADP metabolic process

NADPH regeneration

pentose-phosphate shunt [GO:0006098] (14 genes, 21 annotations)

pentose-phosphate shunt, non-oxidative branch

pentose-phosphate shunt, oxidative branch

regulation of pentose-phosphate shunt

photosynthetic NADP+ reduction

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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