Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF7
  • Mouse genes Rnf7
  • Rat genes Rnf7
  • Zfish genes rnf7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	RNF7	IDA		Human	PMID:10230407
Molecular Function	GO:0061663	NEDD8 ligase activity	RNF7	IDA		Human	PMID:19250909
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q8WXK4	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q9Y576	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q969M7	Human	PMID:19250909
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q9Y6K9	Human	PMID:20098747
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q93034	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q93034	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:P12504	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q93034	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:P12004	Human	PMID:26030842
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q6PH85	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q8IWE4	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q92564	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q96GG9	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q9BTE7	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RNF7	IPI	UniProtKB:Q93034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rnf7	IPI	PR:O35718	Mouse	PMID:15601820
Cellular Component	GO:0031466	Cul5-RING ubiquitin ligase complex	RNF7	IDA		Human	PMID:22405651
Cellular Component	GO:0005737	cytoplasm	Rnf7	IDA		Mouse	PMID:10082581
Cellular Component	GO:0005829	cytosol	RNF7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RNF7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Rnf7	IDA		Mouse	PMID:10082581
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Rnf7	IDA		Mouse	PMID:10082581
Biological Process	GO:0008637	apoptotic mitochondrial changes	Rnf7	IDA		Mouse	PMID:10082581
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Rnf7	IMP		Mouse	PMID:24210661
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Rnf7	IGI	MGI:MGI:108554	Mouse	PMID:24210661
Biological Process	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	Rnf7	IDA		Mouse	PMID:10082581
Biological Process	GO:0043066	negative regulation of apoptotic process	Rnf7	IDA		Mouse	PMID:10082581
Biological Process	GO:0045116	protein neddylation	RNF7	IDA		Human	PMID:19250909
Biological Process	GO:0021942	radial glia guided migration of Purkinje cell	Rnf7	IGI	MGI:MGI:108554	Mouse	PMID:24210661
Biological Process	GO:0021942	radial glia guided migration of Purkinje cell	Rnf7	IMP		Mouse	PMID:24210661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern