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Gene Ontology Browser
Term Detail
GO term:apoptotic mitochondrial changes
GO id:GO:0008637
Definition:The morphological and physiological alterations undergone by mitochondria during apoptosis.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-aorganelle organization
                                        is-amitochondrion organization
                                                is-aapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                        is-amitochondrial fragmentation involved in apoptotic process
                                                        is-amitochondrial outer membrane permeabilization +
                                                        is-arelease of cytochrome c from mitochondria +
                                                        is-arelease of matrix enzymes from mitochondria
                                                is-amitochondrial fission +
                                                is-amitochondrial fusion +
                                                is-amitochondrial genome maintenance +
                                                is-amitochondrial membrane organization +
                                                part-ofmitochondrial protein catabolic process
                                                part-ofmitochondrial proton-transporting ATP synthase complex assembly
                                                part-ofmitochondrial respiratory chain complex assembly +
                                                is-amitochondrial respiratory chain supercomplex assembly
                                                is-amitochondrial RNA processing +
                                                is-amitochondrial translation +
                                                is-amitochondrion distribution +
                                                is-amitochondrion morphogenesis
                                                negatively-regulatesnegative regulation of mitochondrion organization +
                                                positively-regulatespositive regulation of mitochondrion organization +
                                                part-ofprotein targeting to mitochondrion +
                                                regulatesregulation of mitochondrion organization +
                                                is-asperm mitochondrion organization
                                                is-atranscription from mitochondrial promoter +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofactivation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        is-aanoikis +
                                                        part-ofapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                                is-amitochondrial fragmentation involved in apoptotic process
                                                                is-amitochondrial outer membrane permeabilization +
                                                                is-arelease of cytochrome c from mitochondria +
                                                                is-arelease of matrix enzymes from mitochondria
                                                        is-aapoptotic process involved in luteolysis
                                                        is-aapoptotic process involved in metanephric collecting duct development +
                                                        is-aapoptotic process involved in metanephric nephron tubule development +
                                                        is-aapoptotic process involved in morphogenesis +
                                                        part-ofapoptotic signaling pathway +
                                                        is-acell-type specific apoptotic process +
                                                        part-ofexecution phase of apoptosis +
                                                        negatively-regulatesnegative regulation of apoptotic process +
                                                        part-ofnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofnegative regulation of mitochondrial membrane permeability involved in apoptotic process
                                                        positively-regulatespositive regulation of apoptotic process +
                                                        part-ofpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofpositive regulation of mitochondrial membrane permeability involved in apoptotic process +
                                                        regulatesregulation of apoptotic process +
                                                        part-ofregulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofregulation of mitochondrial membrane permeability involved in apoptotic process


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aorganelle organization
                                        is-amitochondrion organization
                                                is-aapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                        is-amitochondrial fragmentation involved in apoptotic process
                                                        is-amitochondrial outer membrane permeabilization +
                                                        is-arelease of cytochrome c from mitochondria +
                                                        is-arelease of matrix enzymes from mitochondria
                                                is-amitochondrial fission +
                                                is-amitochondrial fusion +
                                                is-amitochondrial genome maintenance +
                                                is-amitochondrial membrane organization +
                                                part-ofmitochondrial protein catabolic process
                                                part-ofmitochondrial proton-transporting ATP synthase complex assembly
                                                part-ofmitochondrial respiratory chain complex assembly +
                                                is-amitochondrial respiratory chain supercomplex assembly
                                                is-amitochondrial RNA processing +
                                                is-amitochondrial translation +
                                                is-amitochondrion distribution +
                                                is-amitochondrion morphogenesis
                                                negatively-regulatesnegative regulation of mitochondrion organization +
                                                positively-regulatespositive regulation of mitochondrion organization +
                                                part-ofprotein targeting to mitochondrion +
                                                regulatesregulation of mitochondrion organization +
                                                is-asperm mitochondrion organization
                                                is-atranscription from mitochondrial promoter +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-adeath
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofactivation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        is-aanoikis +
                                                        part-ofapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                                is-amitochondrial fragmentation involved in apoptotic process
                                                                is-amitochondrial outer membrane permeabilization +
                                                                is-arelease of cytochrome c from mitochondria +
                                                                is-arelease of matrix enzymes from mitochondria
                                                        is-aapoptotic process involved in luteolysis
                                                        is-aapoptotic process involved in metanephric collecting duct development +
                                                        is-aapoptotic process involved in metanephric nephron tubule development +
                                                        is-aapoptotic process involved in morphogenesis +
                                                        part-ofapoptotic signaling pathway +
                                                        is-acell-type specific apoptotic process +
                                                        part-ofexecution phase of apoptosis +
                                                        negatively-regulatesnegative regulation of apoptotic process +
                                                        part-ofnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofnegative regulation of mitochondrial membrane permeability involved in apoptotic process
                                                        positively-regulatespositive regulation of apoptotic process +
                                                        part-ofpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofpositive regulation of mitochondrial membrane permeability involved in apoptotic process +
                                                        regulatesregulation of apoptotic process +
                                                        part-ofregulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofregulation of mitochondrial membrane permeability involved in apoptotic process


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofactivation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        is-aanoikis +
                                                        part-ofapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                                is-amitochondrial fragmentation involved in apoptotic process
                                                                is-amitochondrial outer membrane permeabilization +
                                                                is-arelease of cytochrome c from mitochondria +
                                                                is-arelease of matrix enzymes from mitochondria
                                                        is-aapoptotic process involved in luteolysis
                                                        is-aapoptotic process involved in metanephric collecting duct development +
                                                        is-aapoptotic process involved in metanephric nephron tubule development +
                                                        is-aapoptotic process involved in morphogenesis +
                                                        part-ofapoptotic signaling pathway +
                                                        is-acell-type specific apoptotic process +
                                                        part-ofexecution phase of apoptosis +
                                                        negatively-regulatesnegative regulation of apoptotic process +
                                                        part-ofnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofnegative regulation of mitochondrial membrane permeability involved in apoptotic process
                                                        positively-regulatespositive regulation of apoptotic process +
                                                        part-ofpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofpositive regulation of mitochondrial membrane permeability involved in apoptotic process +
                                                        regulatesregulation of apoptotic process +
                                                        part-ofregulation of cysteine-type endopeptidase activity involved in apoptotic process +
                                                        part-ofregulation of mitochondrial membrane permeability involved in apoptotic process


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aorganelle organization
                                        is-amitochondrion organization
                                                is-aapoptotic mitochondrial changes [GO:0008637] (67 genes, 100 annotations)
                                                        is-amitochondrial fragmentation involved in apoptotic process
                                                        is-amitochondrial outer membrane permeabilization +
                                                        is-arelease of cytochrome c from mitochondria +
                                                        is-arelease of matrix enzymes from mitochondria
                                                is-amitochondrial fission +
                                                is-amitochondrial fusion +
                                                is-amitochondrial genome maintenance +
                                                is-amitochondrial membrane organization +
                                                part-ofmitochondrial protein catabolic process
                                                part-ofmitochondrial proton-transporting ATP synthase complex assembly
                                                part-ofmitochondrial respiratory chain complex assembly +
                                                is-amitochondrial respiratory chain supercomplex assembly
                                                is-amitochondrial RNA processing +
                                                is-amitochondrial translation +
                                                is-amitochondrion distribution +
                                                is-amitochondrion morphogenesis
                                                negatively-regulatesnegative regulation of mitochondrion organization +
                                                positively-regulatespositive regulation of mitochondrion organization +
                                                part-ofprotein targeting to mitochondrion +
                                                regulatesregulation of mitochondrion organization +
                                                is-asperm mitochondrion organization
                                                is-atranscription from mitochondrial promoter +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory