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Gene Ontology Browser
Term Detail
GO term:intrinsic apoptotic signaling pathway in response to oxidative stress
Synonym: induction of apoptosis by oxidative stress
Synonym: oxidative stress-induced intrinsic apoptotic signaling pathway
GO id:GO:0008631
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
Number of paths to term: 38

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aapoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aapoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-acell death in response to oxidative stress
                                                is-acell death in response to hydrogen peroxide +
                                                part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                is-aprogrammed cell death in response to reactive oxygen species +
                                                regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofapoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway
                                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to oxidative stress
                                        is-acellular response to oxidative stress
                                                is-acell death in response to oxidative stress
                                                        is-acell death in response to hydrogen peroxide +
                                                        part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                        is-aneuron death in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                        is-aprogrammed cell death in response to reactive oxygen species +
                                                        regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to oxidative stress
                                        is-acellular response to oxidative stress
                                                is-aage-dependent response to oxidative stress involved in chronological cell aging +
                                                is-aage-dependent response to oxidative stress involved in replicative cell aging +
                                                is-acell death in response to oxidative stress +
                                                is-acellular response to hydroperoxide +
                                                is-acellular response to reactive oxygen species +
                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of cellular response to oxidative stress +
                                                is-aoxidative stress-induced premature senescence
                                                positively-regulatespositive regulation of cellular response to oxidative stress +
                                                is-apositive regulation of transcription factor import into nucleus in response to oxidative stress
                                                regulatesregulation of cellular response to oxidative stress +
                                                is-aregulation of transcription from RNA polymerase II promoter in response to oxidative stress +
                                                is-aregulation of translation in response to oxidative stress +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-adeath
                                is-acell death
                                        is-acell death in response to oxidative stress
                                                is-acell death in response to hydrogen peroxide +
                                                part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                is-aprogrammed cell death in response to reactive oxygen species +
                                                regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-adeath
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofapoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway
                                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aapoptotic signaling pathway
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aintrinsic apoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aapoptotic signaling pathway
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aintrinsic apoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                regulatesregulation of intrinsic apoptotic signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-acell death in response to oxidative stress
                                                is-acell death in response to hydrogen peroxide +
                                                part-ofintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                        is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                        negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                        positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                        regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                negatively-regulatesnegative regulation of oxidative stress-induced cell death +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of oxidative stress-induced cell death +
                                                is-aprogrammed cell death in response to reactive oxygen species +
                                                regulatesregulation of oxidative stress-induced cell death +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-aprogrammed cell death
                                                is-aapoptotic process
                                                        part-ofapoptotic signaling pathway
                                                                is-aintrinsic apoptotic signaling pathway
                                                                        is-aintrinsic apoptotic signaling pathway by p53 class mediator +
                                                                        is-aintrinsic apoptotic signaling pathway in response to DNA damage +
                                                                        is-aintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to hypoxia +
                                                                        is-aintrinsic apoptotic signaling pathway in response to nitrosative stress
                                                                        is-aintrinsic apoptotic signaling pathway in response to osmotic stress +
                                                                        is-aintrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631] (38 genes, 43 annotations)
                                                                                is-aintrinsic apoptotic signaling pathway in response to hydrogen peroxide +
                                                                                negatively-regulatesnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                is-aneuron intrinsic apoptotic signaling pathway in response to oxidative stress +
                                                                                positively-regulatespositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                                regulatesregulation of oxidative stress-induced intrinsic apoptotic signaling pathway +
                                                                        negatively-regulatesnegative regulation of intrinsic apoptotic signaling pathway +
                                                                        positively-regulatespositive regulation of intrinsic apoptotic signaling pathway +
                                                                        regulatesregulation of intrinsic apoptotic signaling pathway +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory