Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNASE6
  • Mouse genes Rnase6
  • Rat genes Rnase6
  • Zfish genes rnasel2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnase6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004540	RNA nuclease activity	RNASE6	IDA		Human	PMID:9826755
Molecular Function	GO:0004540	RNA nuclease activity	rnasel2	IDA		Zfish	PMID:16861230
Molecular Function	GO:0004540	RNA nuclease activity	rnasel2	IDA		Zfish	PMID:17347156
Cellular Component	GO:0031410	cytoplasmic vesicle	RNASE6	IDA		Human	PMID:25075772
Cellular Component	GO:0005615	extracellular space	RNASE6	IDA		Human	PMID:25075772
Cellular Component	GO:0005615	extracellular space	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0001525	angiogenesis	rnasel2	IDA		Zfish	PMID:16861230
Biological Process	GO:0019731	antibacterial humoral response	RNASE6	IDA		Human	PMID:25075772
Biological Process	GO:0019731	antibacterial humoral response	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	RNASE6	IDA		Human	PMID:25075772
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0050829	defense response to Gram-negative bacterium	RNASE6	IDA		Human	PMID:25075772
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0050829	defense response to Gram-negative bacterium	rnasel2	IDA		Zfish	PMID:21050179
Biological Process	GO:0050829	defense response to Gram-negative bacterium	rnasel2	IDA		Zfish	PMID:17347156
Biological Process	GO:0050830	defense response to Gram-positive bacterium	RNASE6	IDA		Human	PMID:25075772
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0050830	defense response to Gram-positive bacterium	rnasel2	IDA		Zfish	PMID:21050179
Biological Process	GO:0050830	defense response to Gram-positive bacterium	rnasel2	IDA		Zfish	PMID:17347156
Biological Process	GO:0051607	defense response to virus	RNASE6	IDA		Human	PMID:9826755
Biological Process	GO:0045087	innate immune response	RNASE6	IDA		Human	PMID:25075772
Biological Process	GO:0045087	innate immune response	Rnase6	IDA		Mouse	MGI:MGI:5902674|PMID:25075772
Biological Process	GO:0090501	RNA phosphodiester bond hydrolysis	RNASE6	IDA		Human	PMID:9826755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern