Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGS6
  • Mouse genes Rgs6
  • Rat genes Rgs6
  • Zfish genes rgs6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RGS6	IDA		Human	PMID:10521509
Molecular Function	GO:0005515	protein binding	RGS6	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	Rgs6	IPI	UniProtKB:Q3UVC4	Mouse	PMID:15897264
Molecular Function	GO:0005515	protein binding	Rgs6	IPI	PR:Q8C419	Mouse	PMID:22689652
Molecular Function	GO:0019904	protein domain specific binding	Rgs6	IPI	RGD:69000	Rat	PMID:12140291|RGD:737642
Cellular Component	GO:0005737	cytoplasm	Rgs6	IDA		Rat	PMID:12140291|RGD:737642
Cellular Component	GO:0005829	cytosol	RGS6	IDA		Human	PMID:10521509
Cellular Component	GO:0019898	extrinsic component of membrane	RGS6	IDA		Human	PMID:10521509
Cellular Component	GO:0005794	Golgi apparatus	Rgs6	IDA		Rat	PMID:12140291|RGD:737642
Cellular Component	GO:0032991	protein-containing complex	Rgs6	IDA		Rat	PMID:12140291|RGD:737642
Biological Process	GO:0043547	positive regulation of GTPase activity	RGS6	IDA		Human	PMID:10521509
Biological Process	GO:0045666	positive regulation of neuron differentiation	Rgs6	IDA		Rat	PMID:12140291|RGD:737642

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern