Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGS16
  • Mouse genes Rgs16
  • Rat genes Rgs16
  • Zfish genes rgs16,rgs5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RGS16	IDA		Human	PMID:18434541
Molecular Function	GO:0005096	GTPase activator activity	Rgs16	IDA		Mouse	MGI:MGI:5706919|PMID:10373502
Molecular Function	GO:0005515	protein binding	RGS16	IPI	UniProtKB:P26651	Human	PMID:21784977
Molecular Function	GO:0005515	protein binding	Rgs16	IPI	UniProtKB:P18872-1	Mouse	MGI:MGI:6092643|PMID:18434540
Cellular Component	GO:0005737	cytoplasm	RGS16	IDA		Human	PMID:10791963
Cellular Component	GO:0016020	membrane	Rgs16	IDA		Mouse	MGI:MGI:5706919|PMID:10373502
Cellular Component	GO:0045121	membrane raft	Rgs16	IDA		Rat	PMID:12642593|RGD:1300469
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Rgs16	IDA		Mouse	MGI:MGI:5706919|PMID:10373502
Biological Process	GO:0043547	positive regulation of GTPase activity	RGS16	IDA		Human	PMID:18434541
Biological Process	GO:0043547	positive regulation of GTPase activity	Rgs16	IDA		Mouse	MGI:MGI:5706919|PMID:10373502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern