Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFK
  • Mouse genes Rfk
  • Rat genes Rfk
  • Zfish genes rfk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rfk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RFK	IPI	UniProtKB:P19438	Human	PMID:19641494
Molecular Function	GO:0005515	protein binding	RFK	IPI	UniProtKB:P19438-1	Human	PMID:19641494
Molecular Function	GO:0005515	protein binding	Rfk	IPI	PR:P25118	Mouse	PMID:19641494
Molecular Function	GO:0005515	protein binding	Rfk	IPI	PR:Q3U0V2	Mouse	PMID:19641494
Molecular Function	GO:0008531	riboflavin kinase activity	RFK	IDA		Human	PMID:19641494
Cellular Component	GO:0005739	mitochondrion	Rfk	HDA		Mouse	PMID:18614015
Biological Process	GO:0006915	apoptotic process	RFK	IMP		Human	PMID:19641494
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	RFK	IMP		Human	PMID:19641494
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	Rfk	IGI	MGI:MGI:104798	Mouse	PMID:19641494
Biological Process	GO:0072593	reactive oxygen species metabolic process	Rfk	IGI	MGI:MGI:104798	Mouse	PMID:19641494
Biological Process	GO:0072593	reactive oxygen species metabolic process	Rfk	IGI	MGI:MGI:2156367	Mouse	PMID:19641494
Biological Process	GO:0006771	riboflavin metabolic process	RFK	IDA		Human	PMID:19641494

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern